This case report describes a rare instance of familial congenital atrichia in a 16-year-old girl, possibly involving a genetic component, as both her parents exhibit similar clinical features.
August 2022 in “Scholars academic journal of pharmacy” This study involved formulating an invasome gel loaded with clotrimazole for treating fungal infections and assessed its various properties like spreadability and in vitro drug diffusion.
March 2022 in “Marmara University Open Access System” This article critically examines the relationship between new media and digital games, emphasizing their cultural and historical contexts, but provides no new empirical findings.
This study found that all examined biomarkers and clinical features were elevated in systemic lupus erythematosus patients, particularly ANA and Anti-dsDNA autoantibodies, but no single biomarker was sensitive or specific enough for diagnosis.
January 2022 in “Journal of Biomedical Research & Environmental Sciences” This study suggests that eNOS and STAT6 gene polymorphisms may increase the risk of developing PCOS in South Indian women.
January 2021 in “International Journal of Advanced Research in Medicine” This study observed that propranolol, flunarizine, and divalproex sodium were equally effective in managing migraine across a three-month period in a group of 84 patients, with various side effects noted among the drug groups.
August 2020 in “Egyptian Veterinary Medical Society of Parasitology Journal (EVMSPJ)” In this study, 10.5% of sheep examined in Ismailia, Egypt, were infested with Sarcoptes scabiei, showing specific molecular and skin alterations.
December 2016 in “John Wiley & Sons, Ltd eBooks” This chapter reviews disorders of skin appendages including miliaria, acne, and alopecia, providing guidance on management and treatment but does not present new clinical findings.
This study formulated and evaluated a Hibiscus rosa-sinensis herbal gel, identifying a 20% concentration as superior in physical properties, suggesting its potential as an alternative drug delivery system.
October 2012 in “European Neuropsychopharmacology” This study found that videoconferencing enabled reliable and consistent assessment of negative symptoms in patients with schizophrenia, demonstrating high interrater reliability among blinded independent raters.
This chapter reviews the structure, pharmacokinetics, and clinical applications of PEGylated liposomes and reports no new research findings.
June 2006 in “Annales de Dermatologie et de Vénéréologie” This review highlights the potential benefits of spironolactone in dermatology, particularly for female acne, supporting its safety over long-term use without extensive testing, but presents no new clinical results.
1265 citations
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October 2013 in “The Journal of Clinical Endocrinology and Metabolism” This guideline from the Endocrine Society recommends using the Rotterdam criteria for diagnosing polycystic ovary syndrome and outlines first-line treatments, emphasizing hormonal contraceptives and lifestyle intervention.
1057 citations
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November 2011 in “Annals of Biomedical Engineering” This review discusses the applications of low level laser therapy (LLLT) in wound healing, pain reduction, and treating various conditions, but reports no new clinical results; the authors highlight the need for randomized controlled trials for serious diseases.
658 citations
,
June 2003 in “Endocrine reviews” This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.
474 citations
,
January 2012 in “Chemistry & biology” This review discusses the discovery and potential therapeutic uses of proteasome inhibitors across various diseases, including cancer and autoimmune conditions, but does not present new clinical data.
441 citations
,
May 2008 in “British Journal of Pharmacology” This article reviews the potential clinical use of anabolic steroids in treating muscle loss from chronic diseases and aging and highlights both the benefits and risks of these substances in sports.
425 citations
,
January 2021 in “SN Applied Sciences” This article highlights the versatility and potential of alginate and its derivatives in tissue engineering applications, discussing their properties, modification techniques, and various uses in enhancing tissue healing, bone regeneration, and cell growth.
421 citations
,
January 2015 in “Chemical Society Reviews” This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.
369 citations
,
June 2013 in “Biochimie” This review discusses the potential benefits of myo-inositol supplementation for insulin resistance-related disorders and diabetic complications, but reports no new clinical results.
316 citations
,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.
306 citations
,
April 2019 in “International Journal of Molecular Sciences” This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.
305 citations
,
July 2016 in “International Journal of Biological Macromolecules” This review describes the roles of polysaccharides in antitumor, antiviral, and anti-inflammatory activities and introduces methods for their isolation and purification, reporting no new research results.
305 citations
,
February 2007 in “Hormone and metabolic research” This review discusses the roles of androgens and estrogens in skin functions and disorders, and highlights the use of estrogen-progestin treatments and anti-androgens in managing hirsutism and acne, without reporting new results.
284 citations
,
February 2008 in “Pediatrics” This review discusses the potential impact of endocrine-disrupting chemicals and body size on pubertal onset and progression, highlighting critical gaps and priorities for future research without presenting new clinical results.
280 citations
,
July 2018 in “Antioxidants” This review discusses the role of reactive oxygen species in wound healing, highlighting potential strategies like mitochondrial-targeted antioxidants for managing non-healing chronic wounds, and reports no new clinical results.
275 citations
,
March 1999 in “Journal of The American Academy of Dermatology” This review elaborates on the skin side effects of chemotherapy and emphasizes identifying and managing both common and life-threatening skin reactions, without presenting new clinical findings.
269 citations
,
May 2002 in “Journal of Neuroscience” This study observed that acute stress in rats increased neurosteroid levels linked to enhanced GABA(A) receptor function, raising seizure thresholds, while similar effects were seen in mice with deoxycorticosterone administration.
268 citations
,
April 2009 in “International Journal of Pharmaceutics” In this study, niosomal formulations enhanced minoxidil skin accumulation compared to commercial and control solutions, suggesting a potential improvement for topical delivery in hair loss treatment.
262 citations
,
May 2017 in “Nanomedicine” This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.