March 2007 in “Journal of Plastic Reconstructive & Aesthetic Surgery” A new method was developed to create better skin models for healing and reconstruction.
June 1996 in “Journal of Dermatological Science” 47 citations
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April 2001 in “Journal of Dermatological Science” This study found that insulin-like growth factor-I and hepatocyte growth factor increased the chemotactic migration of human hair outer root sheath cells, suggesting these factors have both growth stimulatory and chemotactic effects.
33 citations
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April 2020 in “Journal of Clinical Investigation” This study found that hair follicle stem cells from hidradenitis suppurativa patients showed alterations in cell cycle regulation and DNA replication, potentially linking genetic predisposition to the skin inflammation characteristic of the disease.
25 citations
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July 1994 in “Journal of dermatological science” This study observed that testosterone metabolism and androgen receptor localization differ significantly across body sites, with beard hair follicles showing distinct characteristics compared to occipital scalp hair follicles.
21 citations
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April 2018 in “Journal of Dermatological Science” This study found that topical cilostazol promotes hair growth, enhances hair follicle activities, and may serve as a potential treatment for alopecia.
14 citations
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June 2018 in “Frontiers in pharmacology” In this study, EGCG from green tea promoted mink hair follicle growth and cell proliferation at specific concentrations, potentially through activation of Shh and AKT signaling pathways.
9 citations
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June 2020 in “BMC Molecular and Cell Biology” This study found that stress hormones, particularly CRF, can inhibit hair growth and induce hair loss by affecting human dermal papilla cells and hair follicles, suggesting a functional HPA axis in these cells.
6 citations
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January 1994 in “Skin Pharmacology and Physiology” This study suggests that the attachment and interaction between dermal papillae and the hair bulb matrix are crucial for normal hair follicle growth and development in vitro.
5 citations
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January 2017 in “Molecular Medicine Reports” This study found that nestin-negative hair follicle stem cells can differentiate into neural stem cell-like cells, but not mature neurons, through a multi-step neuro-induction process.
1 citations
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July 2019 in “Small ruminant research” This study suggests that the NGF/TrkA/CREB system plays a crucial role in promoting outer root sheath cell proliferation in cashmere goats, which may aid in marker-assisted breeding.
February 2024 in “Journal of Dermatological Science” This study examined the formation of acquired curved hair and found that the fusion of hair matrix cells during follicle regeneration contributes to asymmetric follicle shapes and curved hair, potentially linked to changes in type IV collagen and protein expression levels.
April 2025 in “International Journal of Pharmaceutical Sciences Review and Research” This study found that SesZen-Bio TM, a proprietary extract from Sesbania grandiflora leaves, increased proliferation of hair cells and hair shaft length in vitro and ex vivo, potentially due to activation of the Wnt/β-catenin signaling and stem cell differentiation pathways.
August 2024 in “Archives of Dermatological Research” This study suggests that proteins CHI3L1 and CXCL5, secreted by recovery-state dermal papilla cells, may promote hair growth by stimulating the proliferation of outer root sheath cells.
January 2024 in “Biological & pharmaceutical bulletin” In this study, Panax ginseng extract and its ginsenosides were found to stimulate the proliferation of hair-related cells and promote the transition from the telogen to the anagen phase, enhancing hair-shaft growth by suppressing BMP4 expression in human dermal papilla cells.
June 2014 in “Biotechnology and Bioprocess Engineering” This study demonstrated that injecting reconstructed dermal papilla-like tissues in mice led to new hair growth, suggesting potential future applications in hair transplantation and baldness treatment.
This study reported that a skin equivalent model using human outer root sheath cells and fibroblasts showed the formation of structures similar to human dermis and epidermis within two weeks after transplantation into mice.
March 2026 in “Journal of Bioscience and Bioengineering” Oxytocin from hair cells helps hair growth and stem cell increase.
25 citations
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September 2018 in “Scientific Reports” This study found that morroniside enhanced hair follicle growth and transition through the Wnt/β-catenin signaling pathway in a mouse model, suggesting its potential as a treatment for hair loss.
2 citations
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January 2022 in “International Journal of Medical Sciences” In this study, kartogenin promoted hair growth by enhancing cell proliferation and migration in vitro and extended hair length in mice, suggesting its potential as a treatment for hair loss.
1 citations
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January 2020 in “Seoul National University Open Repository (Seoul National University)” This study found that a phosphodiesterase 3 inhibitor promoted hair growth in human dermal papilla cells and stimulated anagen induction in mice, suggesting potential as a treatment for alopecia.
1 citations
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January 2009 in “Journal of Dermatology and Venereology” This study found that cells from the upper hair follicle exhibited more active growth compared to other segments in vitro, suggesting their potential as a source of hair follicle stem cells.
2 citations
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July 2025 in “Consilium Medicum” This study found that in women with alopecia, anxiety levels significantly decreased with temgikoluril alongside standard therapy over 12 weeks, enhancing emotional well-being and treatment satisfaction compared to the control group receiving only standard therapy.
1 citations
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February 2024 in “Journal of Modern Oncology” This study found that scalp hypothermia effectively prevented chemotherapy-induced alopecia in 57.3% of breast cancer patients, with side effects such as a feeling of cold and slight headaches reported in 16% of cases.
1 citations
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August 2021 in “Consilium Medicum” In this study, the use of Selencin, both in tablet and peptide lotion form, over two months showed significant improvements in reducing hair loss and restoring hair structure and volume in patients with diffuse alopecia, with effects persisting up to four months after treatment.
September 2025 in “Consilium Medicum” This study discusses the role of 5α-reductase inhibitors in managing lower urinary tract symptoms caused by benign prostatic hyperplasia and suggests their potential use in other conditions like prostate cancer chemoprevention and androgenetic alopecia treatment, emphasizing appropriate dosing to reduce surgical complications.
July 2025 in “Consilium Medicum” In this study, women with telogen effluvium showed significant improvement in hair loss and hair growth density when treated with a combination of oral Pantovigar, a Microxidil-containing topical lotion, and mesotherapy with a placental preparation compared to those not receiving Pantovigar.
October 2024 in “Consilium Medicum” This article reviews current understanding of dermal fibroblasts' structure and function, highlighting their crucial role in connective tissue formation and repair, which is important for selecting effective treatments for age-related skin changes.
February 2024 in “Journal of Modern Oncology” In this study, researchers found that using the Orbis II scalp cooling device in a single-center setting effectively prevented severe chemotherapy-induced alopecia in 73% of patients with various cancer types, though the authors recommend further studies to explore broader applicability and influencing factors.
December 2021 in “Consilium Medicum” This study found that treating diffuse alopecia associated with prior COVID-19 infection using a combination of Selencin (homeopathic drug) and Selencin Peptide Active (peptide lotion) significantly reduced hair loss and improved hair structure and volume in 34 patients over two months.