85 citations
,
June 2008 in “Annals of the New York Academy of Sciences” This article proposes a hypothesis that hyperandrogenemia is the final common pathway for developing adolescent PCOS and emphasizes the importance of reducing androgen levels to mitigate risks of metabolic syndrome, diabetes, and infertility in adulthood.
5 citations
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November 2001 in “PubMed” This case report describes an 80-year-old woman with severe androgenic alopecia linked to Leydig cell hyperplasia in an ovarian cyst, highlighting the need to investigate androgen-secreting tumors in similar cases.
1 citations
,
September 2023 in “Journal of Education Health and Sport” This study provides a comprehensive analysis of anabolic-androgenic steroids, reporting that their use enhances muscle mass but is associated with significant health issues including cardiac muscle hypertrophy, liver disease, and changes in gender characteristics, emphasizing the need for patient awareness of these risks.
September 2008 in “Fertility and Sterility” This study found that infertile couples who perceive themselves as having high intimacy report better subjective health, particularly in fulfilling social responsibilities and maintaining physical fitness.
6 citations
,
August 2013 in “Fertility and Sterility” This study found that cream ingestion increased NFκB activation in women with PCOS, which was associated with insulin resistance and higher ovarian androgen levels, regardless of obesity status.
This study found that irregular menstrual cycles and weight gain were common among women with PCOS, with 87% and 64% of patients experiencing these symptoms, respectively.
1 citations
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January 2017 in “Tohoku journal of experimental medicine” This study reports the first case of ovarian mature cystic teratoma linked to clinical virilization due to ectopic testosterone production, possibly from overexpression of the enzyme HSD17B5.
October 2025 in “Journal of the Endocrine Society” In this case report, a transgender woman with refractory epilepsy began estrogen therapy for gender-affirming purposes, experiencing stable epilepsy and reduced gender dysphoria through ongoing multidisciplinary care, highlighting the importance of careful management for similar patients.
2 citations
,
February 2023 in “BMC women's health” In this study, oral contraceptive use in women with PCOS increased the expression of certain inflammatory gene markers, which were positively associated with metabolic abnormalities.
18 citations
,
March 2015 in “Journal of Endocrinological Investigation” This study found that ZP4 expression was highest among PCOS patients with regular menstrual cycles, which may be linked to mature follicle presence, but no correlation with clinical indices was observed.
47 citations
,
December 2016 in “Scientific Reports” This study found that women with PMS were more likely to use suppression rather than reappraisal for emotion regulation, and increased suppression was linked to higher skin conductance levels in these women.
24 citations
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March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
6 citations
,
November 1980 in “Clinical Endocrinology” This study measured plasma testosterone glucosiduronate levels and found no overlap in those with hyperandrogenism compared to normal females, despite normal testosterone and dihydrotestosterone levels in half of the affected patients.
May 2021 in “Journal of the Endocrine Society” This study found that while 11-oxyandrogens do not aid in diagnosing PCOS, they correlate with hirsutism severity, and 11-ketotestosterone levels decrease with combined oral contraceptive therapy.
5 citations
,
January 2023 in “International Journal of Environmental Research and Public Health” This study found that women with PCOS who reported the highest levels of physical activity also reported better outcomes in BMI, mental health, and sleep quality, suggesting that enhancing motivation may improve participation in physical activity.
202 citations
,
January 1989 in “Journal of Clinical Investigation” This study indicates that insulin changes sex hormone levels in insulin-resistant women with polycystic ovary syndrome without affecting gonadotropin release, challenging the idea that hyperinsulinemia directly causes hyperandrogenism in PCO.
1 citations
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October 2024 in “Cureus” This study reported that women with polycystic ovarian syndrome have higher serum irisin levels, which are associated with metabolic and hormonal imbalances, including hyperandrogenism, total cholesterol, and visceral fat.
January 2026 in “International Journal of Women s Health” This study found that a nomogram prediction model based on clinical characteristics, bone metabolism, and ovarian function can effectively predict the treatment response to long-acting GnRHa in girls with idiopathic central precocious puberty.
May 2026 in “The Bioscan.” This review explores the potential benefits of using medicinal plants as an alternative or supplementary therapy for improving reproductive and metabolic health in women with polycystic ovary syndrome, but reports no new results.
This review discusses the diagnostic criteria and management challenges for polycystic ovarian syndrome and reports no clinical results, highlighting complications associated with pregnancy in women with the condition.
10 citations
,
January 2004 in “KARGER eBooks” This article reviews the differential diagnosis of mild hyperandrogenism in adolescent girls, discussing potential causes such as PCOS and nonclassic adrenal hyperplasia, but presents no new data.
2 citations
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January 2005 in “PubMed” In this study, females with hirsutism showed higher levels of certain androgens and reported more frequent symptoms such as infertility and increased skin greasiness compared to those without hirsutism.
60 citations
,
April 1998 in “Baillière s Clinical Endocrinology and Metabolism” This article reviews the genetic mutations causing male pseudohermaphroditism from 17 beta-HSD-3 and 5 alpha-RD-2 deficiencies and reports no new clinical findings.
2 citations
,
February 2022 in “Pakistan Armed Forces Medical Journal” This study found that women with PCOS reported significant appearance-related distress and social anxiety, especially in social settings.
January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This article reviews the polycystic ovary syndrome as a polyendocrine disease, detailing its etiology, pathogenesis, and research methods, but presents no new clinical results.
July 1993 in “学術講演梗概集. A, 材料施工,防火,海洋,情報システム技術” This study observed that hyperprolactinemia in women may be associated with skin and hair symptoms similar to those induced by androgens, suggesting hormone level evaluations in such cases.
7 citations
,
January 2024 in “Medicinska istrazivanja” This review outlines the complexities and varied manifestations of polycystic ovary syndrome, highlighting challenges in diagnosis and management but reports no new clinical findings.
49 citations
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May 2018 in “Endocrine” This study found that only eumenorrheic polycystic ovary syndrome patients showed a temporal coupling between kisspeptin and luteinizing hormone pulsatile secretions.
23 citations
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January 1997 in “Computers and Composition” This article discusses the dynamics of the "mole gaze" and cybersexism on the Web, analyzing interactions through personal and theoretical lenses, and suggests the need for both structural and psychological change to counteract these issues.
September 1997 in “Journal of the European Academy of Dermatology and Venereology” Hirsute women with ovarian-sourced hirsutism are more likely to have irregular periods, with higher BMI and altered hormone ratios.