TLDR PCOS is a major health issue affecting multiple hormone-producing organs.
Polycystic Ovary Syndrome (PCOS) is highlighted as a significant issue in gynecological endocrinology, characterized as a polyendocrine disorder involving dysfunctions in the pancreas, adrenal cortex, ovaries, hypothalamus, and pituitary gland. The article provides detailed information on the etiology, pathogenesis, clinical symptoms, and the laboratory and instrumental methods used for research on PCOS.
222 citations
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January 2014 in “International journal of reproductive medicine” Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
44 citations
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September 2020 in “International Journal of Molecular Sciences” New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
218 citations
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December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
December 2023 in “Research in pharmacy” Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).
16 citations
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February 2018 in “BMC Genomics” Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.