November 2024 in “Frontiers in Medicine” In this review, the researchers highlighted the prevalent symptoms in cirrhosis patients, including pain, muscle cramps, sleep disturbances, and mental health issues, and emphasized the need for a comprehensive, multidisciplinary approach for symptom management to improve quality of life.
April 2024 in “Middle East Fertility Society Journal” In this study of infertile Indonesian women with PCOS, researchers found no correlation between hirsutism, body measurements, and sexual dysfunction scores, but noted that hirsutism may be linked to higher anxiety levels.
March 2024 in “Healthcare” In this study, women with androgenetic alopecia underwent stem cell treatment, which led to significant improvements in sexual arousal and satisfaction, psychological health, and environmental quality of life, but not in physical health or social relationships after six months.
November 2023 in “Frontiers in Neuroendocrinology” This study suggests that post-finasteride syndrome and post-SSRI sexual dysfunction share potential etiopathogenetic mechanisms involving brain modulators, neurotransmitters, and gut microbiota, although more research is needed to understand these conditions fully.
October 2023 in “Georgetown medical review” This review found that both finasteride and dutasteride are effective for treating hair loss in men with androgenetic alopecia, with dutasteride showing higher efficacy, but noted unclear clinical significance regarding potential negative impacts on reproduction, including possible sexual dysfunction and effects on spermatogenesis.
July 2023 in “Dermatology and Therapy” This review analyzed the use of 5-alpha reductase inhibitors (5ARIs) for treating various dermatological conditions such as androgenetic alopecia, acne, and hirsutism, emphasizing their efficacy and safety profile.
February 2023 in “IntechOpen eBooks” This article discusses the various administration methods and considerations for testosterone replacement therapy, highlighting the importance of individualized therapeutic monitoring and potential adverse effects, but reports no new clinical results.
November 2022 in “IntechOpen eBooks” This review discusses the psychiatric approach to treating alopecia patients and highlights the interplay between psychological factors and hair disorders, but reports no new research results.
October 2022 in “Biomolecules” This study found that in male rats, chronic finasteride treatment reduced allopregnanolone levels, which, upon drug withdrawal, correlated with increased pro-inflammatory cytokines and altered neurotransmitter levels.
January 2017 in “Indian journal of sexually transmitted diseases and AIDS” Finasteride, a hair loss drug, can cause sexual side effects like erectile dysfunction in 2.1%-3.8% of users, but these usually go away with time or if the drug is stopped. Despite this, its impact on sexual function is minimal for most men.
1 citations
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November 2006 in “Medicina de Familia SEMERGEN” February 2026 in “The Journal of Sexual Medicine” In this case report, goserelin, a GnRH agonist, was effective in managing stuttering priapism and improving erectile function in a patient with sickle cell disease, suggesting potential for last-line treatment.
October 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This piece describes the EndoPump Male Enhancement supplement, which claims to enhance erections and libido, but notes that there is insufficient medical evidence supporting the efficacy of its ingredients for sexual health.
9 citations
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April 2007 in “Journal of Andrology” This article reviews the management of excessive pre-ejaculate, highlighting case reports where 5-α-reductase inhibitors, such as finasteride and dutasteride, led to symptom resolution in patients reporting distress due to this condition.
4 citations
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September 2020 in “Andrologia” This study found that Origanum vulgare extract improved testicular structure and function in mice against finasteride-induced damage by enhancing antioxidant defense and modulating gene expression related to apoptosis.
January 2025 in “Haematology International Journal” This study describes a functional disorder in the ovary, known as stromal hyperplasia, characterized by the proliferation of ovarian stroma and luteinization of stromal cells, which is linked to excessive androgen production and elevated testosterone levels.
May 2022 in “The Journal of Sexual Medicine” In this retrospective study at Toyama University Hospital, amoxapine was reported to significantly improve semen volume, sperm concentration, and total sperm count in 17 men with ejaculatory disorders, with no observed side effects over an average of 13 months of therapy.
October 2022 in “Amplla Editora eBooks” October 2025 in “Journal of Obstetric and Gynaecological Practices POGS”
2 citations
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August 2021 in “The Journal of Urology” This study reported that seminal vesiculoscopy combined with transurethral resection of ejaculatory ducts and balloon dilation effectively resolved hematospermia and improved symptoms in a patient whose condition was unresponsive to medical treatments.
May 2024 in “Reactions weekly”
15 citations
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August 2022 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” This pilot study found that intraovarian platelet-rich plasma administration significantly improved the euploidy rate of embryos in infertile women with previous IVF failures.
1 citations
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January 1999 in “Theriogenology” 28 citations
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November 2009 in “European Journal of Neuroscience” This study found that progesterone can increase glycine release in rat brainstem neurons through its conversion to allopregnanolone, which modulates presynaptic GABA receptor activity.
10 citations
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February 1976 in “The Journal of Dermatology” This study found that topical γ‐Oryzanol significantly stimulated sebaceous gland cell activity and sebum production in rats.