research Melatonin
Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
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research Adenosine A2B Receptor: A Pathogenic Factor and a Therapeutic Target for Sensorineural Hearing Loss
Blocking adenosine A2B receptor may prevent or treat hearing loss.
research CAQ Corner: Basic Concepts of Transplant Immunology
The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
research The Skin as an Endocrine Organ
The skin produces and processes hormones, affecting both local and overall body functions.
research Alopecia Areata Update
Despite progress in treatment, the exact cause of Alopecia areata is still unknown.
research Alopecia Areata Presenting in Two Kidney-Pancreas Transplant Recipients Taking Cyclosporine
Two transplant patients on cyclosporine unexpectedly developed hair loss.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research Adrenal 21-Hydroxylase Gene Mutations in Slovenian Hyperandrogenic Women: Evaluation of Corticotrophin Stimulation and HLA Polymorphisms in Screening for Carrier Status
The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.
research Low Disease Activity—Irrespective of Serologic Status at Baseline—Associated with Reduction of Corticosteroid Dose and Number of Flares in Patients with Systemic Lupus Erythematosus Treated with Belimumab: A Real-Life Observational Study
Belimumab reduces disease activity, steroid use, and flares in lupus patients.
research Dermatological Manifestations Associated with COVID-19: A Comprehensive Review of the Current Knowledge
COVID-19 can cause various skin issues, including rashes and hair loss, which usually heal on their own and don't always indicate severe illness.
research Management of Hair Problems
Dr. Vera H. Price's 1979 work emphasizes the importance of accurate diagnosis and personalized treatment for hair loss.
research Recognition and Management of Staphylococcus Aureus Toxin-Mediated Disease
Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.
research Treatment of Hyperandrogenism in Women
Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
research Harnessing Neuroendocrine Controls of Keratin Expression: A New Therapeutic Strategy for Skin Diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research Urinary Steroid Analysis of Women with Effluvium
Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.
research The Role of Dexamethasone in Mediating the Contradictory Effects of Wnt Antagonists SFRP2 and SFRP3 on Human Hair Follicle Growth
Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.
research Probing the Effects of Stress Mediators on the Human Hair Follicle
Stress-related substance P may lead to hair loss and negatively affect hair growth.
research Prolactin: A Novel Neuroendocrine Regulator of Human Keratin Expression In Situ
Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
research Sarcoidosis: Are There Differences in Your Skin of Color Patients?
Sarcoidosis is more common and severe in Black patients than in Caucasians, requiring early diagnosis and treatment.
research Psychological Stress-Induced Pathogenesis of Alopecia Areata: Autoimmune and Apoptotic Pathways
Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.
research Sebocytes’ Makeup: Novel Mechanisms and Concepts in the Physiology of the Human Sebaceous Glands
Hormones and signaling pathways control sebaceous gland function and could help treat acne.
research Comprehensive Overview of Rheumatology Studies: Ottawa, Ontario, Canada, February 13–16, 2013
The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
research Steroid Hormones: Overview and Medical Applications
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
research Late-Onset Systemic Lupus Erythematosus
Older adults diagnosed with lupus show less severe symptoms but have a lower survival rate, often due to age-related factors.
research Profiling the Response of Human Hair Follicles to Ultraviolet Radiation
UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
research Dermatologic Care of the Transplant Patient
Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.
research Electron Microscope Studies of Hair and Wool
Hair and wool have complex microscopic structures with microfibrils and varying cystine content.
research Steroidogenesis of the Testis: New Genes and Pathways
New genes and pathways are important for testosterone production and male sexual development.
research Comparison of Systemic Mycophenolate Mofetil with Topical Clobetasol in Lichen Planopilaris: A Parallel-Group, Assessor- and Analyst-Blinded, Randomized Controlled Trial
Topical clobetasol is recommended over mycophenolate mofetil for treating Lichen Planopilaris due to better safety and patient satisfaction.
research Cutaneous Toxicities of New Treatments for Melanoma
New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.