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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Finasteride causes lasting fertility decrease in rats.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Estrogen therapy helped regrow hair in a bald man.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

COVID-19 may harm male fertility and damage the reproductive system.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Finasteride reduces movement issues in Parkinson's disease rats.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Finasteride doesn't affect erections much, but may decrease libido in men.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Male-pattern baldness might be caused by the effect of hormones on scalp blood vessels.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Hair loss drugs may cause sexual issues and infertility in men.

Androgen deprivation therapy might be better for preventing COVID-19 than treating it.

Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

No definitive link between finasteride and male breast cancer, but further research is needed.

Younger transgender women have surgery earlier, are mostly attracted to men, and show more preoperative depression that improves after surgery compared to older transgender women.

Finasteride reduces melanin production, possibly treating hyperpigmentation and melanoma, but needs more safety research.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

New ABCA12 gene mutations were linked to a skin condition with scaling and hair loss, and a treatment helped with hair loss in a related case.