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Orthognathic surgeons play a key role in modifying masculine facial features to be more feminine, often improving transgender women's quality of life.

Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.

Research on hair disorders has advanced, with promising future progress in understanding and treating these conditions.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.

Blocking JAK-STAT signaling can lead to hair growth.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Hair loss linked to higher heart disease risk in both men and women.

New treatments targeting specific genes show promise for treating keratin disorders.