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The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

The Rotterdam Study aims to understand various diseases in older adults.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Sebocytes play a key role in controlling androgen levels in human skin.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Minoxidil effectively lowers blood pressure with few side effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Scalp dermoscopy is good for diagnosing a type of hair loss and helps choose the best spots for biopsy.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Finasteride safely lowers DHT levels without affecting testosterone.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Most women with hirsutism or androgenic alopecia had polycystic ovaries, especially if they had irregular periods.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.