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Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

The article concludes that understanding the molecular processes in hair follicle development can improve the quality of fibers like Angora and cashmere.

Eating healthy, exercising, and certain nutrients like myoinositol and omega-3s can help manage PCOS symptoms.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Finasteride negatively affects fish reproduction and gonadal development.

Dihydrotestosterone treatment on 2D and 3D-cultured skin cells slows down hair growth by affecting certain genes and could be a potential target for hair loss treatment.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

Early detection and comprehensive treatment of PCOS are crucial due to its long-term health impacts and associated risks.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.

HDAC6 helps keep ovarian follicles dormant, extending female fertility.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

PCOS treatment focuses on lifestyle changes and specific medications to manage symptoms and complications.

Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.