2 citations
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January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.
January 2014 in “Ghent University Academic Bibliography (Ghent University)” FGF18 may influence hair loss in dogs.
29 citations
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July 2010 in “Journal of Cutaneous Medicine and Surgery” This study reported no significant improvement in patients with frontal fibrosing alopecia treated with various therapeutic agents, highlighting the need for more evidence-based treatments, especially in those with active disease.
1 citations
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January 2014 in “Hair therapy & transplantation” This report describes benefits of advanced hair transplant techniques, micro-FUE and U-FUE, which may result in natural, undetectable hair restoration and discrete post-procedure appearance.
8 citations
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August 2014 in “Biochemical and Biophysical Research Communications” The study found that over-expressing ornithine decarboxylase in the outer root sheath of the hair follicle in mice increases UVB-induced tumor growth and invasive squamous cell carcinoma compared to inter-follicular epidermal keratinocytes.
25 citations
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December 2017 in “Facial Plastic Surgery” This study observed that combining high-potency steroids with pimecrolimus might effectively stabilize hairline recession in frontal fibrosing alopecia patients.
June 2026 in “Advanced Science” This study demonstrated that novel cryomicroneedles loaded with hair follicle organoids (cryoMN@HFOs) can effectively deliver and develop into functional hair follicles after intradermal transplantation in animal experiments, suggesting promising potential for human hair follicle reconstruction.
September 1994 in “Otolaryngology-Head and Neck Surgery” This article contains news and announcements related to Otolaryngology–Head and Neck Surgery but provides no new research findings.
1 citations
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May 2013 in “Hair transplant forum international” Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.
2 citations
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October 2015 in “Obstetrics and gynaecology cases - reviews” This case report details a postmenopausal woman with increased libido, hirsutism, and spontaneous orgasms, noting elevated testosterone levels and enlarged ovaries.
August 2018 in “Journal of the American Academy of Dermatology” April 2025 in “International Journal of Dermatology” This article proposes renaming frontal fibrosing alopecia to frontal fibrosing alopecia syndrome to better reflect its varied presentations and enhance understanding and treatment approaches.
28 citations
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June 1995 in “The Journal of Dermatology” This study reports that flaky skin mice exhibit skin and nail features that closely resemble human psoriasis vulgaris, suggesting they may serve as a natural model for this condition.
1 citations
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May 2013 in “Oncology Times” This narrative review reflects on the challenges faced by FDA's Oncologic Drugs Advisory Committee members, highlighting public pressure, decision-making complexity, and the evolving landscape of cancer drug development.
31 citations
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January 2016 in “Skin Appendage Disorders” This study observed two cases of frontal fibrosing alopecia developing on preexisting vitiligo, suggesting a potential causal link between the two conditions.
2 citations
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July 2022 in “Frontiers in Medicine” This review discusses the current understanding of frontal fibrosing alopecia's pathogenesis, highlighting genetic susceptibility, immune response involvement, and possible links to steroid hormones, but reports no new clinical results.
March 2024 in “Biochimica et biophysica acta. Molecular basis of disease” This study found that deferoxamine may protect against sensorineural hearing loss by reducing oxidative stress-induced hair cell death through iron chelation and activation of the Nrf2 signaling pathway in lab models.
32 citations
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February 1993 in “British Journal of Clinical Pharmacology” This study found that OPC-17116 can be reliably detected in hair, suggesting it can serve as an index of drug exposure and a time-marker in hair analysis.
2 citations
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April 2023 in “Cutis” This systematic review discusses the treatment characteristics and outcomes for frontal fibrosing alopecia specifically in Black patients with skin of color, addressing a gap in clinical evidence due to underrepresentation in studies.
December 2015 in “Actas Dermo-Sifiliográficas” This review addresses the challenges in treating frontal fibrosing alopecia, highlighting the limited effectiveness of medical treatments and the demand for hair transplantation despite its risks, but it reports no new clinical results.
April 2016 in “Expert opinion on orphan drugs” This review explores current therapeutic options for frontal fibrosing alopecia, noting the use of finasteride, topical tacrolimus, hydroxychloroquine, and excimer laser in managing the condition, but reports no new clinical results.
1 citations
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January 2013 in “Hair therapy & transplantation” This study reported that adding the topical product CG210 to oral finasteride 1mg significantly increased hair diameter more than finasteride alone in male androgenetic alopecia patients already stabilized on finasteride treatment.
6 citations
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July 2017 in “Clinical and Experimental Dermatology” This report presents four new cases of follicular porokeratosis, which exhibit distinct histological features where the cornoid lamella are confined to the follicular ostia.
7 citations
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January 2019 in “Australasian Journal of Dermatology” In this study, the CYP 21A2 gene p.V281L mutation was associated with an increased susceptibility to familial frontal fibrosing alopecia, suggesting an antigen-driven mechanism linked to certain human leukocyte antigen haplotypes.
5 citations
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March 2014 in “Journal of The American Academy of Dermatology” The study suggests hormonal factors may play a role in Frontal Fibrosing Alopecia and that treatments like oral antiandrogens and steroids could be beneficial.
August 2016 in “Journal of Investigative Dermatology” This study observed that the osteopontin-derived peptide FOL-005 inhibited hair growth in human scalp skin models, contrary to its hair growth promotion in mice, supporting further clinical testing for excessive hair growth treatment.
September 2020 in “Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi” This review investigates the relationship between certain gene polymorphisms associated with obesity (FTO and MC4R) and Polycystic Ovarian Syndrome, reporting no new results but suggesting a potential genetic link.
February 2011 in “Journal of the American Academy of Dermatology” This study found that polycystic ovary syndrome was the most common cause of hirsutism among premenopausal women in Algeria.
22 citations
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March 1963 in “Archives of dermatology” This case report describes hair regrowth in a patient with alopecia totalis using fluocinolone acetonide cream applied under thin plastic films.
1 citations
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October 2014 in “Skin Pharmacology and Physiology” This study found that osteopontin expression was significantly higher in alopecia areata lesions compared to healthy controls, suggesting it may play a role in the disease's pathogenesis.