research Dermatologic Adverse Events from Cancer Treatments
Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.
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research Ascorbigen Induces Dermal Papilla Cell Proliferation In Vitro, But Fails To Modulate Chemotherapy-Induced Alopecia In Vivo
Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.
research Development and Validation of Androgen-Induced Hair Loss and Anagen Induction Mouse Models for Pharmacological Evaluation of Anti-Androgenic Agents
The mouse models are effective for testing new hair loss treatments.
research Pilar Cyst From a Maxillofacial Surgeon's Perspective: A Case Report and Review of Literature
A man had a benign pilar cyst on his face, which is rare and was successfully removed by surgery.
research Regenerative Potential and Clinical Application of Mesenchymal Stem Cell-Derived Exosomes
MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.
research Keratinocytes and Adipose-Derived Mesenchymal Stem Cells: The Heir and the Spare to Regenerative Cellular Therapies for Difficult-to-Heal Skin Wounds
Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.
research Periungual Lesions Secondary to Chemotherapy with Docetaxel
Chemotherapy with docetaxel can cause painful nail and skin side effects that may lead to stopping treatment.
research Tofacitinib Citrate Alleviates Alopecia Universalis Symptoms in Recent Case Study
Tofacitinib helped a person with total body hair loss grow hair again without bad side effects.
research Image Guided Radiotherapy in Stage III Prostate Cancer: Analysis of Acute Toxicity
IGRT resulted in lower acute toxicity for stage III prostate cancer patients.
research Innovations in Chemotherapy and Radiation Therapy: Implications and Opportunities for the Asia-Pacific Rim
New cancer treatments are more precise and less toxic, improving survival rates, but Asia faces challenges in adopting these advancements.
research COVID-19 and Sex Differences: Mechanisms and Biomarkers
Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
research Congenital Adrenal Hyperplasia: Current Insights in Pathophysiology, Diagnostics, and Management
Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
research Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection
Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
research Drug-Induced Skin, Nail, and Hair Disorders
Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.
research Pegylated Liposomal Doxorubicin in the Treatment of Breast Cancer
PLD is an effective and safer alternative for treating breast cancer.
research Dermal White Adipose Tissue: A New Component of the Thermogenic Response
Skin fat helps with body temperature control and has other active roles in health.
research Targeted Gene Delivery to Skin Cells In Vivo: A Comparative Study of Liposomes and Polymers as Delivery Vehicles
Nonionic liposomes are the best for delivering genes to skin cells.
research Photodynamic and Photobiological Effects of Light-Emitting Diode Therapy in Dermatological Disease: An Update
LED therapy is safe and shows potential for treating skin conditions and promoting hair growth, but more research is needed.
research Profiling the Response of Human Hair Follicles to Ultraviolet Radiation
UVB radiation harms hair growth and health, causing cell death and other changes in human hair follicles.
research Mitoxantrone
Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
research Semiology of Skin Toxicity Associated with Epidermal Growth Factor Receptor Inhibitors
Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex
An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
research Phenotypic Variability Associated with WNT10A Nonsense Mutations
WNT10A mutations cause varied symptoms in patients with odonto-onycho-dermal dysplasia.
research Graphene Oxide–IPDI–Ag/ZnO@Hydroxypropyl Cellulose Nanocomposite Films for Biological Wound-Dressing Applications
The new nanocomposite films are stronger, protect against UV, speed up wound healing, and are antibacterial without being toxic.
research Progesterone-Induced Stimulation of Mammary Tumorigenesis Is Due to the Progesterone Metabolite, 5α-Dihydroprogesterone (5αP), and Can Be Suppressed by the 5α-Reductase Inhibitor, Finasteride
Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
research Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane-Induced Dystrophy and Redirect Polyunsaturated Fatty Acid Metabolism Toward β-Oxidation
Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.
research iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration
Early-stage skin cells help regenerate hair follicles, with proteins SDF1, MMP3, biglycan, and LTBP1 playing key roles.
research Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes
Mechlorethamine treatment regrew hair in mice by killing immune cells causing hair loss without harming hair follicles.
research Insertional Mutation of the Hairless Locus on Mouse Chromosome 14
A gene mutation in mice causes permanent hair loss and skin issues.
research Identification of Finasteride Metabolites in Human Bile and Urine by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.