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The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

Apple extract called procyanidin B-2 was found to greatly increase hair growth.

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

Skin organoids are a promising new model for studying human skin development and testing treatments.

PI3K/Akt pathway is crucial for hair growth and regeneration.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

Patients with GATA2 deficiency show early skin symptoms that help diagnose the condition.

The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.

Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.

Ozone therapy might improve cancer treatment and reduce its side effects.

Crataegus pinnatifida extract may help increase hair growth and thickness in mice.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.

The document concludes that veterinary dermatologists need more experience and a better approach to treating skin diseases in nonhuman primates.

Early diagnosis and aggressive treatment are crucial for better outcomes in lymphomatoid granulomatosis.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.