22 citations
,
September 2015 in “Fertility and Sterility” In this study, abnormal glucose tolerance was found to be prevalent among young Indian women with PCOS, and the use of an oral glucose tolerance test significantly improved its detection.
40 citations
,
January 2010 in “Annales D Endocrinologie” This article discusses diagnostic guidelines for PCOS, emphasizing the use of the Rotterdam criteria and recommending clomiphene citrate as the first-line treatment for ovulation induction; it reports no new clinical results.
6 citations
,
August 2023 in “European journal of endocrinology” This review discusses the 2023 International Guideline for PCOS assessment and management, highlighting updated evidence-based recommendations and practice points aimed at improving care and health outcomes, but notes that research quality remains generally low to moderate.
19 citations
,
January 2019 in “Ginekologia Polska” This study found that combined Myo-inositol and D-chiro-inositol therapy improved metabolic and hormonal parameters, including weight, hormone levels, and skin conditions, in women with PCOS after 6 months.
4025 citations
,
December 2003 in “Human Reproduction” This review discusses the evolution of diagnostic criteria for polycystic ovary syndrome and emphasizes its association with various metabolic and cardiovascular risks, but it provides no new research findings.
116 citations
,
December 2013 in “European journal of endocrinology” This study found that combining liraglutide with metformin led to greater weight loss and waist circumference reduction than either treatment alone in obese women with PCOS resistant to metformin monotherapy.
22 citations
,
January 2012 in “Obstetrics and Gynecology International” In this study of Bulgarian women, the waist-to-stature ratio was a better marker for an unfavorable metabolic profile than the waist-to-hip ratio among those with PCOS and obesity.
8 citations
,
June 2017 in “Hormone Molecular Biology and Clinical Investigation” This study found that subclinical hypothyroidism had minimal impact on the metabolic and hormonal profiles of women with polycystic ovary syndrome.
7 citations
,
March 2011 in “Hormone and Metabolic Research” This study found that in PCOS patients, variations in the lipin 1 gene, particularly the intron 1 SNP, may protect against insulin resistance and glucose intolerance, highlighting a potential genetic factor in the disorder's cardiometabolic complications.
7 citations
,
May 2007 in “PubMed” This study found that women with androgenetic alopecia were more insulin resistant than healthy controls, suggesting the use of beta cell function and insulin sensitivity indices to measure insulin resistance in this population.
6 citations
,
April 2016 in “Journal of the Formosan Medical Association” This study found that metformin treatment improved clinical outcomes in Taiwanese women with polycystic ovary syndrome, notably in overweight and insulin-resistant patients.
92 citations
,
May 2014 in “The American Journal of Medicine” This review discusses the multi-system impacts of polycystic ovary syndrome and explores evaluation and treatment strategies, but it reports no new research findings.
3 citations
,
March 2007 in “Canadian Medical Association Journal” This abstract provides background information on polycystic ovary syndrome and reports no new research findings.
October 2018 in “The American Journal of Gastroenterology” This case report highlights a rare instance of late dumping syndrome following fundoplication in an adult, diagnosed using an oral glucose tolerance test, illustrating its potential for reducing diagnostic delays.
49 citations
,
March 2009 in “Archives of Gynecology and Obstetrics” This study found that age, pre-pregnancy BMI, and family history of diabetes were independent predictors of gestational diabetes in Iranian women, with selective screening missing few cases among low-risk groups.
30 citations
,
March 2001 in “Environmental Health Perspectives” This review explores the significant impacts of hormonal changes within normal physiological ranges and suggests examining low-dose effects from chemicals disrupting hormonal activity; it presents no new clinical results.
2 citations
,
March 2001 in “Environmental Health Perspectives” Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.
16 citations
,
February 2016 in “Gynecological Endocrinology” This study observed two distinct phenotypes among North Indian women with PCOS: obese hyperinsulinaemic dysglycemic women from Delhi and lean hyperandrogenic women from Srinagar, despite being in the same region.
198 citations
,
July 2011 in “Cochrane library” This study found that lifestyle interventions improved body composition, hyperandrogenism, and insulin resistance in women with PCOS, but did not affect glucose tolerance, lipid profiles, or clinical reproductive outcomes.
75 citations
,
July 2013 in “The Journal of Clinical Endocrinology and Metabolism” This study found that combining low-dose spironolactone with metformin provided greater clinical benefits and improved treatment compliance in women with PCOS compared to either drug alone.
61 citations
,
January 2015 in “Hormones” In this study, short-term liraglutide treatment led to significant weight loss in obese women with newly diagnosed PCOS and a higher metabolic risk profile compared to metformin.
53 citations
,
December 2015 in “JAMA Dermatology” This study found that hirsutism and acanthosis nigricans are the most reliable skin markers for diagnosing polycystic ovary syndrome in women and suggest a need for further evaluation of possible metabolic issues.
42 citations
,
September 2007 in “The Journal of Clinical Endocrinology and Metabolism” This study found that women with PCOS who have an exaggerated 17-hydroxyprogesterone response to buserelin exhibit more severe hyperandrogenemia, increased insulin secretion, and reduced insulin sensitivity.
19 citations
,
January 2017 in “Hormone Molecular Biology and Clinical Investigation” This study found a high prevalence of hyperandrogenemia in women with PCOS, with distinct biochemical differences according to BMI and presence of hyperandrogenemia.
18 citations
,
January 2015 in “Journal of obesity and weight loss therapy” This study found that an 8-week low-starch/low-dairy diet led to weight loss, improved insulin sensitivity, and reduced testosterone levels in women with PCOS.
16 citations
,
April 2007 in “Journal of Obstetrics and Gynaecology Research” In this study, serum PSA levels were higher in women with PCOS, suggesting it may serve as a marker for hyperandrogenism in this condition.
14 citations
,
August 2014 in “Applied Physiology, Nutrition, and Metabolism” This study concluded that an 8-week low-starch/low-dairy diet increased fat oxidation in overweight and obese women with PCOS.
11 citations
,
October 2018 in “Hormone and Metabolic Research” This study found no difference in bone mineral density between young women with PCOS and age- and BMI-matched controls, but BMI significantly influenced BMD in women with PCOS.
6 citations
,
July 2016 in “Gynecological Endocrinology” This study found that women with PCOS have higher total PSA levels than controls, and the total PSA level correlates positively with testosterone and free androgen index.
5 citations
,
October 2018 in “Journal of Clinical Laboratory Analysis” This study found that improved testosterone measurement using LC-MS/MS in women with PCOS revealed a stronger correlation between hyperandrogenism and insulin resistance than previously detected.