August 2018 in “Journal of The American Academy of Dermatology” The conclusion is that finasteride is linked to an increased risk of suicidal thoughts and a higher risk of completed suicide when used for hair loss.
November 2021 in “Evidencia” In this study, the use of finasteride in young patients may be linked to a higher risk of anxiety, depression, and suicide-related adverse events.
37 citations
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December 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that black and Hispanic women had higher odds of self-reported alopecia areata compared to white women, highlighting potential racial disparities in the condition's occurrence.
34 citations
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June 2014 in “The BMJ” This study found that children with intracranial injuries had significantly lower odds of achieving satisfactory early academic performance compared to those without head injuries.
29 citations
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May 2016 in “Journal of the American Academy of Dermatology” This study observed that patients with alopecia areata had decreased odds of developing stroke and a potential decreased risk of acute myocardial infarction, though the latter was not statistically significant.
24 citations
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December 2011 in “Journal of The American Academy of Dermatology” This study observed that melanoma survivors had higher odds of using sunscreen and seeking shade compared to cancer-free individuals, but their overall adherence to sun protection was less than expected given their elevated risk for new skin cancers.
16 citations
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April 2018 in “Current opinion in gynecology and obstetrics” The study observed that Hispanic women with PCOS had significantly higher odds of having NASH compared to non-Hispanic women, suggesting routine screening may be beneficial in this high-risk group.
10 citations
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August 2022 in “Journal of clinical sleep medicine” This study found that transgender or gender-nonconforming youth experience higher odds of sleep disorders compared to cisgender peers, but gender-affirming therapy may reduce these odds.
June 2026 in “British Journal of Dermatology” This study found that individuals with frontal fibrosing alopecia have increased odds of thyroid disease, lupus erythematous, vitiligo, and heart disease, supporting the consideration of FFA as a systemic disorder.
September 2024 in “Journal of the American Academy of Dermatology” This meta-analysis found that smoking is significantly associated with increased odds of developing and progressing androgenetic alopecia, with higher risks observed in men smoking at least 10 cigarettes daily.
April 2023 in “Journal of Investigative Dermatology” This study found that alopecia areata patients have higher odds of certain comorbidities like ulcerative colitis and vitiligo, while showing lower odds for conditions like hypertension and type 2 diabetes compared to healthy controls.
February 2020 in “Pharmacoepidemiology and Drug Safety” This study found that finasteride users had higher odds of testicular abnormalities, obesity, and other conditions, highlighting the need for confounder adjustment in studies on its association with male breast cancer.
18 citations
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September 2020 in “BMC Public Health” This study found that non-Kuwaiti COVID-19 patients in Kuwait had higher odds of death, ICU admission, ARDS, and pneumonia compared to Kuwaiti patients.
17 citations
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October 2020 in “Journal of Clinical Medicine” In this study, Koreans with rosacea showed higher odds of experiencing various systemic comorbidities, including autoimmune diseases and certain cancers, compared to controls.
7 citations
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July 2025 in “International Journal of Dermatology” This meta-analysis found that patients with alopecia areata have significantly higher odds of also having immune-mediated diseases such as atopic dermatitis, autoimmune thyroiditis, inflammatory bowel disease, systemic lupus erythematosus, and vitiligo, suggesting a need for comprehensive screening and interdisciplinary management.
January 2026 in “Journal of Epidemiology” This cross-sectional study reported that adults with greater hair loss severity had significantly higher odds of hypertension, diabetes, and cardiometabolic multimorbidity, suggesting a possible link between hair loss and cardiometabolic health.
January 2024 in “Wiadomości Lekarskie” This study found that engaging in outdoor physical activities significantly reduced the odds of increased HbA1C levels, lower HDL-cholesterol, and obesity among patients with metabolic syndrome, suggesting potential health benefits for this population.
June 2020 in “Research Square (Research Square)” This study found that non-Kuwaiti COVID-19 patients in Kuwait had higher odds of death, ICU admission, ARDS, and pneumonia compared to Kuwaiti patients.
87 citations
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May 2012 in “PLOS Genetics” This study found that early-onset androgenetic alopecia in individuals of European ancestry is significantly associated with increased odds of Parkinson's disease and is influenced by specific genetic loci, including some linked to reduced fertility.
19 citations
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November 2021 in “Lupus Science & Medicine” This study found that Black patients with discoid lupus erythematosus had significantly worse CLASI damage scores and higher odds for dyspigmentation, scalp involvement, and scarring alopecia compared to non-Black patients.
6 citations
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August 2020 in “Dermatology and Therapy” This study found that patients with alopecia areata had significantly lower serum vitamin D levels and higher odds of vitamin D deficiency, but no significant difference in serum calcium levels, compared to controls.
5 citations
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July 2019 in “Nutrients” This study found that boys in Mexico City with selenium intake below the recommended dietary allowance had lower odds of progressing to advanced stages of pubertal development, while no association was observed in girls.
August 2026 in “The Laryngoscope” This study found that adults with type 2 diabetes or obesity using semaglutide and tirzepatide experienced higher odds of nonscarring alopecia, such as telogen effluvium, compared to those using other GLP-1 receptor agonists, with hair loss potentially linked to physiologic stress from weight loss.
September 2024 in “Journal of the American Academy of Dermatology” In this retrospective case-control study, researchers reported that patients with alopecia areata had significantly increased odds of venous thromboembolism compared to matched controls, suggesting a potential association between alopecia areata and risk of VTE.
December 2023 in “JEADV Clinical Practice” This study found that dermoscopy of the axilla in patients with frontal fibrosing alopecia revealed significantly higher odds of brownish peripillary halos, suggesting a diagnostic clue for the condition in this region.
November 2023 in “International Journal of Dermatology” In this study, CCCA patients were found to have higher odds of metabolic, autoimmune, atopic, and psychiatric comorbidities compared to matched controls.
April 2023 in “Journal of Investigative Dermatology” This study provides an updated systematic review and meta-analysis showing that alopecia areata is associated with significantly higher odds of several autoimmune and metabolic comorbidities compared to healthy controls.
20 citations
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March 2017 in “Arthritis research & therapy” In this study, researchers analyzed social media data to assess the comparative safety of arthritis medications, finding increased odds of herpes zoster and perforated bowel with certain therapies. Social media posts expressed more safety concerns than favorable opinions about drug safety.
13 citations
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April 2018 in “Journal of The American Academy of Dermatology” This study found that 64.8% of patients with different types of alopecia had vitamin D deficiency, and those with lichen planopilaris and telogen effluvium had higher odds of severe deficiency compared to patients with alopecia areata.
11 citations
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April 2023 in “Annals of General Psychiatry” This study found that males treated with serotonergic antidepressants had an increased risk of erectile dysfunction, with an adjusted odds ratio of 3.2, and the risk for post-SSRI sexual dysfunction was 0.46%, emphasizing the importance of informed consent due to these potential irreversible side effects.