Systemic Comorbidities in Korean Patients with Rosacea: Results from a Multi-Institutional Case-Control Study

The study examined the link between rosacea and systemic comorbidities in Korean patients, involving 12,936 rosacea patients and an equal number of controls. It found that rosacea patients had higher odds of having autoimmune diseases like Sjögren syndrome and alopecia areata, cancers such as lung and hepatobiliary cancer, and conditions like obesity, alcohol abuse, and various allergic and infectious disorders. Gender and age influenced the prevalence of specific comorbidities, with women more likely to have autoimmune diseases and men more prone to alcohol abuse. The study underscored the need for clinicians to consider these associations in managing rosacea patients.