4 citations,
March 2020 in “BMC Research Notes” Skin tags in obese individuals may indicate higher cardiovascular risk.
1 citations,
February 2021 in “International journal of reproduction, contraception, obstetrics and gynecology” Polycystic Ovary Syndrome (PCOS) is common in infertile women and obese women with PCOS have more severe ovulatory problems, needing more care.
114 citations,
January 2014 in “World Journal of Gastroenterology” People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.
70 citations,
April 2013 in “Endocrine” Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.
37 citations,
October 2004 in “Adolescent Medicine Clinics” Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.
5 citations,
October 2022 in “Cureus” Older, obese people with many COVID-19 symptoms are more likely to suffer from severe long-term COVID-19 effects.
June 2021 in “Health and Society” Healthy lifestyle changes, especially weight loss, can improve symptoms and overall health in people with Polycystic Ovary Syndrome, especially if they are overweight or obese.
54 citations,
April 2007 in “Gastroentérologie clinique et biologique” Bariatric surgery can worsen nutritional deficiencies, requiring careful monitoring and supplementation.
December 2022 in “Journal of Sulaimani Medical College” Sleeve gastrectomy leads to significant weight loss and health improvements with few complications.
October 2017 in “Indian heart journal” Obesity is an independent risk factor for early coronary artery disease (CAD) and its severity is not affected by age.
January 2022 in “Menoufia Medical Journal” Obesity can cause various skin problems, with differences in prevalence between males and females.
October 2020 in “Cirugía y cirujanos” Obesity is linked to more severe lower urinary tract symptoms.
October 2017 in “Indian heart journal” Higher levels of small, dense LDL cholesterol are linked to a greater risk of heart attack in young adults.
9 citations,
May 2017 in “Gynecological Endocrinology” Transvaginal hydrolaparoscopy is effective for increasing ovulation and pregnancy rates in women with PCOS who didn't respond to clomiphene.
69 citations,
December 2005 in “Nature Clinical Practice Endocrinology & Metabolism” Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
61 citations,
June 2016 in “Clinical Medicine” PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.
5 citations,
September 2021 in “Dermatology Reports” Skin problems like acne and excess hair in PCOS are common and linked to being overweight.
4 citations,
February 2011 in “Nature Reviews Endocrinology” Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.
3 citations,
January 2013 in “Egyptian Liver Journal” Many young Egyptian women with PCOS also have fatty liver disease, especially if they are overweight and insulin resistant.
January 2009 in “Side effects of drugs annual” Some blood-thinning medications can increase the risk of bleeding, and certain factors like genetics and other health conditions affect their safety and effectiveness.
1265 citations,
October 2013 in “The Journal of Clinical Endocrinology and Metabolism” The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
89 citations,
November 2014 in “Medical Clinics of North America” Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.
59 citations,
August 2021 in “Frontiers in Endocrinology” GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.
43 citations,
May 1986 in “Clinics in Endocrinology and Metabolism” Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.
40 citations,
January 2010 in “Annales D Endocrinologie” The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.
38 citations,
January 2011 in “Endocrine Journal” Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
36 citations,
September 2014 in “Paediatric drugs” More pediatric-specific research and guidelines are needed to improve hidradenitis suppurativa treatment in children and adolescents.
33 citations,
April 2002 in “Journal of Cutaneous Medicine and Surgery” Eating disorders can cause skin problems that need treating the underlying condition for better health.
26 citations,
January 2016 in “Indian journal of endocrinology and metabolism” Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.
16 citations,
October 2020 in “Lipids in Health and Disease” Leptin affects skin and hair health and may worsen some skin conditions, but more research is needed to understand its full impact.