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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Blocking JAK-STAT signaling can lead to hair growth.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Fat cells in the skin help start healing and form important repair cells after injury.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Nerves and chemicals in the body can affect hair growth and loss.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

Minoxidil treats high blood pressure and side effects can be managed.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.