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The NUDT15 R139C variant causes thiopurine-induced leukocytopenia through a different mechanism than previously thought in Japanese patients with inflammatory bowel disease.

The document concludes that the discussed biological mechanisms and potential therapies are not related to hair loss or hair growth.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

The study found that variations in hair protein genes are likely due to evolutionary deletions or duplications.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

Certain genetic variations in the A2M gene are linked to better milk quality in Murrah buffaloes.

Metabolites and diet affect hair growth cycles in cashmere goats.

Hair follicle development in cashmere goats involves dynamic changes in proteins and metabolites, with key roles for oxytocin, MAPK, and Ca2+ pathways.

Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

The EDAR gene greatly affects hair thickness in Asian populations.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

A gene variation is linked to hair thickness in Asians.

The gene KAP22-1 affects wool yield and fiber shape in sheep.

Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.

Certain DNA variants can predict straight hair in Europeans but are not highly specific.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

Certain genetic variations in the FST gene are linked to better wool quality in Chinese Merino sheep.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

No strong genetic link to other skin conditions was found, but some genetic factors may make people more likely to get seborrheic dermatitis.

Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.

Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.

IL16 gene variations may affect the risk of alopecia areata in Koreans.

A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.