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Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.

Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.

Dosing time affects finasteride's effectiveness and safety in rats.

Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Minoxidil boosts hair growth by increasing blood flow and nutrients to hair follicles.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Mutant mice help researchers understand hair growth and related genetic factors.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.

Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.

Autophagy is important for human hair growth and health.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Ozone therapy might improve cancer treatment and reduce its side effects.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.