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Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Nuclear shape and chromatin changes affect gene expression in skin cell differentiation.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

Aryl hydrocarbon receptor overexpression found in miniaturized hair follicles in female hair loss.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Baricitinib reduces inflammation and improves cell health in premature aging cells.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Melatonin may reduce skin damage caused by X-rays in rats.

Alternating treatment with two drugs could help cells in a rapid aging disease.

BMPs are crucial for hair growth and their decrease by androgens leads to hair loss.

Mechanical forces are crucial for shaping cells and forming tissues during development.

Vitamin D3 affects cell differentiation in specific skin areas.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.