research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
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research Clinical Impact of Molecular Diagnostics in Endocrinology
Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.
research Molecular Docking Simulation Studies on Potent Butyrylcholinesterase Inhibitors Obtained from Microbial Transformation of Dihydrotestosterone
Metabolite 7 is a strong inhibitor for Alzheimer's disease management.
research 5α-Reductase Inhibitors: A New Hope in Dermatology?
Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.
research Characterization of DNA Methylation and Screening of Epigenetic Markers in Polycystic Ovary Syndrome
DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.
research Evaluation of Hair Regrowth by Cyclosporine and Minoxidil Using C3H Mouse Model
Cyclosporine starts hair growth faster, while minoxidil makes it last longer.
research Dihydroartemisinin Attenuates Benign Prostatic Hyperplasia in Rats by Inhibiting Prostatic Epithelial Cell Proliferation
Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.
research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes
A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
research Effect of Dihydrotestosterone on the Upregulation of Inflammatory Cytokines in Cultured Sebocytes
Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.
research Effects of 17-β-Estradiol and ICI 182 780 on Hair Growth in Various Strains of Mice
17-β-Estradiol applied to the skin stops hair growth, while ICI 182 780 helps hair grow in mice.
research Female Pattern Hair Loss
Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
research Androgenetic Alopecia: A Review
Male pattern baldness involves genetics, hormones, and needs better treatments.
research 5 Alpha-Reductase Inhibitory Potential of Solanum Nigrum for Alopecia Management
Solanum nigrum may help treat hair loss.
research Androgens Downregulate BMP2, Impairing the Inductive Role of Dermal Papilla Cells on Hair Follicle Stem Cells Differentiation
Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
![Activity of 17β-(N-Alkyl/Arylformamido) and 17β-[(N-Alkyl/Aryl) Alkyl/Arylamido]-4-Methyl-4-Aza-5α-Androstan-3-Ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear](/images/research/861159f1-7bd4-420c-a16b-4829458efe68/small/15592.jpg)
research Activity of 17β-(N-Alkyl/Arylformamido) and 17β-[(N-Alkyl/Aryl) Alkyl/Arylamido]-4-Methyl-4-Aza-5α-Androstan-3-Ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear
The compounds tested could potentially treat hair loss and alopecia.
research Evaluation of 5α-Reductase Inhibitory Activity of Certain Herbs Useful as Antiandrogens
Some herbs show promise as antiandrogenic agents.
research Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study
Eriocitrin and silymarin might be effective for hair loss treatment and need more research.
research Evaluation of the Effects of Adding an Adipose Tissue-Derived Stromal Vascular Fraction to Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia: A Randomized Clinical Trial
Adding stromal vascular fraction to platelet-rich plasma injections did not significantly improve hair growth in androgenetic alopecia treatment.
research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer
Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
research Environmental Endocrine Disrupting Chemicals and Their Epigenetic Influence on Androgenetic Alopecia
Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.
research An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary Oil
Rosemary oil may effectively treat hair loss with fewer side effects, but more research is needed.
research Assessing Medication Use Patterns Among Patients With Polycystic Ovary Syndrome at a Tertiary Care Teaching Hospital in South Korea: A Retrospective Study
Most patients with PCOS were prescribed medroxyprogesterone acetate or oral contraceptives, with some experiencing side effects or needing prescription changes.
research Finasteride Blocks Progesterone Synthesis in MA-10 Leydig Tumor Cells
Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
research Female Pattern Hair Loss: An Update
Female pattern hair loss has multiple causes and treatments, with new therapies showing promise.
research Finasteride
Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
research Finasteride: A Slow-Binding 5-Alpha-Reductase Inhibitor
Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.
research Saw Palmetto
Saw palmetto can help with prostate issues and may promote hair growth.
research Different Gene Expression Profile Observed in Dermal Papilla Cells Related to Androgenic Alopecia by DNA Macroarray Analysis
Hair loss in balding individuals is linked to changes in specific hair growth-related genes.
research Higher Levels of Steroidogenic Acute Regulatory Protein and Type I 3β-Hydroxysteroid Dehydrogenase in the Scalp of Men with Androgenetic Alopecia
Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.
research Hormonal Changes in Menopause: Do They Contribute to a Midlife Hair Crisis in Women?
Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.