13 citations
,
April 1982 in “The Journal of Dermatology” This study found that poly(adenosine diphosphate-ribose) synthesis in human skin varies by cell type and condition, with distinct patterns in psoriatic, cancerous, and normal tissues.
12 citations
,
June 2020 in “Frontiers in Cell and Developmental Biology” This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.
12 citations
,
December 2002 in “Archives of Dermatology” This case report describes a 49-year-old woman with Sweet syndrome who experienced complete resolution of skin lesions after a prednisone treatment regimen.
11 citations
,
May 2012 in “Genesis” This study in mutant mice found that Bmpr2 and Acvr2a are individually redundant, but together essential for normal hair follicle development, with their reduction causing rapid hair cycling and graying.
11 citations
,
February 2003 in “Baillière's best practice & research. Clinical obstetrics & gynaecology/Baillière's best practice and research in clinical obstetrics and gynaecology” This review discusses the relationship between acne, body hair, and androgenic stimulation in adolescent girls, emphasizing treatment decisions based on disease severity rather than endocrine findings.
5 citations
,
August 2015 in “Bioscience, Biotechnology, and Biochemistry” In this study, ob/ob mice were found to have a prolonged telogen hair cycle phase from 10 to 24 weeks, suggesting their potential as a model for studying telogen effluvium.
2 citations
,
July 2015 in “Journal of Dr. YSR University of Health Sciences.” This case report describes a 22-year-old female with pseudoglucagonoma syndrome, where necrolytic migratory erythema resolved after treatment with topical steroids, emollients, and intravenous protein infusions, despite normal glucagon levels and absence of a glucagon-secreting tumor.
2 citations
,
March 2015 in “Human & Experimental Toxicology” This study found that hyperbaric oxygen treatment in rats led to structural changes in epidermis and dermis, including decreased E-cadherin expression and increased connective tissue.
1 citations
,
May 2022 in “International journal of molecular sciences” This study found that in Hutchinson–Gilford progeria syndrome, iPSCs committed to the keratinocyte lineage faster than normal cells, with LEF1 expression reduced and a partial rescue of the phenotype achieved through adenine base editing.
1 citations
,
October 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that depleting HIF-P4H-2 in FoxD1-lineage cells in mice led to disrupted hair follicle development, resulting in truncal alopecia but normal cranial hair, suggesting its crucial role in hair homeostasis.
1 citations
,
January 2020 in “Indian journal of dermatology, venereology, and leprology” This study found that the expression of CD117 and platelet-derived growth factor receptor α differs in alopecia areata tissue compared to normal controls, with platelet-derived growth factor receptor α correlating with disease severity.
1 citations
,
January 2016 in “Elsevier eBooks” This chapter discusses the composition, biocompatibility, and production methods of biomaterials like collagen, chitin, and silk for dermal substitutes, focusing on preclinical and clinical research, but reports no new clinical results.
1 citations
,
October 1984 in “Clinics in dermatology” This article discusses the psychological impact of skin imperfections and suggests establishing a Cosmetic Dermatology Service within public health systems to address these issues ethically.
1 citations
,
February 1977 in “Archives of Dermatology” This case report describes a 2-month-old infant with a severe seborrhea-like skin eruption and respiratory distress, similar to symptoms that led to a sibling's death from Gram-negative septicemia.
September 2024 in “MedComm” This study by Bansaccal et al. found that skin with higher levels of type I collagen density and elasticity in the dermis can inhibit basal cell carcinoma development and spread by acting as a natural barrier against cell reprogramming in mice.
May 2023 in “Experimental Dermatology” In this viewpoint, researchers discussed the possible role of the developmental origin of scalp dermis in influencing the specific pattern of hair follicle miniaturization seen in male pattern hair loss, noting that frontal follicles are more susceptible while occipital follicles remain largely terminal.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study describes a new method for isolating intact human eccrine glands from scalp follicular units, potentially advancing research on sweat gland physiology.
November 2017 in “Pediatrics in Review” This case study identifies early-onset trichotillomania in a 4-year-old girl, treated with behavioral interventions that led to decreased hair pulling and regrowth over three months.
This chapter provides an overview of terminology for various skin lesions, including primary and secondary types, but does not report new findings or results.
October 2015 in “Reactions Weekly” A woman got a scalp condition from using latanoprost, but it improved after stopping the drug and starting other treatments.
1 citations
,
January 2018 in “Journal of cosmetology & trichology” This study found that a new hair loss lotion containing various cosmetic ingredients significantly increased total hair fibers and anagen hairs in individuals with androgenetic alopecia and telogen effluvium, while also improving visual hair characteristics and receiving positive user feedback without adverse effects.
January 2017 in “International journal of transplantation & plastic surgery” This article reviews the historical development and advancements in hair transplant techniques, from punch grafting in the 1950s to the modern follicular unit extraction, and reports no new clinical results.
34 citations
,
September 2020 in “Clinical, cosmetic and investigational dermatology” This research found that hyaluronic acid increased cell proliferation and type I collagen more effectively than poly-L-lactic acid in both human fibroblast cultures and rat dermis.
3 citations
,
January 2012 in “Elsevier eBooks” Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
18 citations
,
September 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that vitamin D-upregulated protein 1 (VDUP1) might play a unique role in regulating the differentiation of epidermal cells.
June 2022 in “Al-Qadisiyah Journal of Veterinary Medicine Sciences” This study found that 660 nm laser treatment and povidone iodine both eradicated Pseudomonas aeruginosa infection in mice wounds, with the laser enhancing healing, and the combination provided additive or synergistic healing benefits.
January 2022 in “Consultant” The man's occipital hair loss was due to temporal triangular alopecia, not alopecia areata.
280 citations
,
July 2018 in “Antioxidants” This review discusses the role of reactive oxygen species in wound healing, highlighting potential strategies like mitochondrial-targeted antioxidants for managing non-healing chronic wounds, and reports no new clinical results.
211 citations
,
April 2013 in “Development” In this study, researchers found that the number of dermal papilla cells in hair follicles determines hair size and shape in mice, suggesting potential avenues for addressing hair loss.
184 citations
,
November 2014 in “Developmental Cell” This study identifies a bipotent stem cell in adult hair follicles that self-renews and contributes to dermal sheath and papilla cell populations, potentially aiding hair regrowth after injury, disease, or aging.