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PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Over 40% of postmenopausal women experience hair loss, with treatments aiming to stop further loss and possibly thicken hair.

MPA increases cancer spread by boosting Eph A2 activity.

The guide explains how to diagnose and treat hair loss in dogs, covering causes and treatments, with some conditions lacking treatment options.

Understanding skin patterns can help us learn about skin diseases and their treatments.

Newer retinoid drugs are effective for skin conditions but have significant side effects.

Cyclosporine starts hair growth faster, while minoxidil makes it last longer.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Growing human skin cells in a 3D environment can stimulate new hair growth.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.