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In this study, researchers reported that both progestin-only injectable contraceptives, DMPA-IM and NET-EN, significantly decreased serum testosterone and SHBG levels among HIV-negative women in South Africa, yet this did not explain prior findings of no reduction in risky sexual behavior or sexual function.

This study developed a spring-driven microneedle booster that improved early and cumulative delivery of minoxidil, accelerating hair regrowth compared to traditional roller methods in an androgenetic alopecia model.

This case report describes an 8-year-old girl with Mixed Connective Tissue Disease who experienced remission after treatment with immunomodulator drugs, highlighting the diagnostic value of anti-U1 RNP antibody testing in children.

In this in vitro study, niacinamide was found not to stimulate VEGF synthesis across a wide range of doses.

A woman experienced excessive hair growth after using a hair loss treatment with minoxidil.

This study found that a microneedle patch containing tofacitinib-loaded nanoparticles significantly increased hair follicle numbers and promoted hair regeneration with less drug compared to daily topical tofacitinib, suggesting it may be an effective strategy for alopecia treatment by reducing dosing frequency and enhancing drug delivery.

Hydroxychloroquine effectively treated twenty-nail dystrophy in a patient with alopecia areata.

This review highlights the potential of near-infrared light therapy to improve metabolic, antioxidant, and cognitive functions without adverse effects, and supports its use for visual and neurological conditions through molecular and cellular mechanisms, as reported in this source.

This article reviews skin toxicity classifications and management in patients undergoing molecularly targeted therapy, noting significant dermatotropic side effects associated with Epidermal Growth Factor Receptor Inhibitors.

This study found that radiofrequency microneedling significantly enhanced the absorption of topical triamcinolone acetonide, with insertion depth being more influential than RF energy levels.

In this study, 755-nm alexandrite laser treatment significantly reduced acne keloidalis nuchae lesions in male patients, improving quality of life and showing low recurrence rates, with temporary hair loss as a reversible complication.

This study found that two novel nonsteroidal derivatives inhibited specific enzymes in vitro and in vivo, leading to dihydrotestosterone accumulation in androgen-dependent glands, suggesting potential therapeutic use for mood improvement in the elderly.

This article discusses the late presentation of myotonic dystrophy but reports no new clinical findings.

In this study, a DMG-Na and caffeine-containing shampoo significantly reduced hair loss and increased hair density in men with male pattern hair loss over 6 months, compared to a placebo, without adverse effects.

This case report describes a patient with breast cancer who developed female androgenetic alopecia after starting tamoxifen therapy.

In this study, researchers developed ionizable coenzyme Q10-engineered lipid/fiber microplexes that restored mitochondrial-ribosomal function and enhanced mRNA translation in senescent cells, leading to increased hair follicle density and bone formation in mouse models compared to conventional lipid nanoparticles.

This study found that photodynamic therapy achieved permanent removal of nonpigmented hair in mice after multiple sessions, unlike laser treatment, which was not effective for nonpigmented hair.

This review examines the potential of nanotechnology-based drug delivery systems to enhance melatonin's therapeutic effectiveness by overcoming its biopharmaceutical limitations, summarizing recent preclinical advancements and addressing clinical translation challenges for treating various diseases.

This review highlights the need for tailored hormonal treatment strategies for non-binary transgender individuals, emphasizing personalized care to enhance psychological well-being and quality of life.

This study found that group behavior therapy for trichotillomania led to greater short-term symptom improvement compared to supportive therapy, but did not achieve clinically significant changes or prevent relapse over six months.

This study developed nanoliposomes embedding AR-PROTAC and NFKBIZ siRNA to target androgen receptors and reduce oxidative stress, which improved the follicular microenvironment and enhanced hair regrowth in androgenetic alopecia, suggesting a promising multi-target therapeutic strategy.

This review highlights the potential of transcranial photobiomodulation (tPBM) as a non-invasive and affordable treatment for brain diseases, summarizing recent advances and successful protocols based on over two decades of research.

In these two clinical trials, DS-2325a, a KLK5 inhibitor, was found to be generally safe and well tolerated in healthy volunteers, with mild and non-serious adverse events, suggesting its potential for further development as a treatment for Netherton Syndrome.

In this pilot study, researchers found that ex vivo treatment with topical melatonin reduced chemotherapy-induced apoptosis and DNA damage in hair follicle stem cells of human scalp cultures, suggesting melatonin's potential as a protective agent against taxane-induced permanent hair loss.

In this case report, combination therapy with topical tretinoin, topical and intralesional steroids, and systemic doxycycline showed improvement in AKN lesions for a 19-year-old man, with notable reductions in lesion size and number observed by the second week.

This study developed a gas-propelled microneedle patch with puerarin/quercetin nanoparticles, which demonstrated improved hair-regenerating effects in an androgenetic alopecia mouse model by increasing drug delivery, alleviating oxidative stress, promoting angiogenesis, and rejuvenating senescent cells.

The LTF gene may help predict and manage nonspecific orbital inflammation.

This abstract describes the Dermatologic Surgery journal, which publishes comprehensive and up-to-date information on various dermatologic surgery techniques such as cosmetic and reconstructive procedures, skin cancer surgeries, and more, making it a valuable resource for professionals in the field.

This review discusses the scalp microinfusion MMP® technique for hair loss treatment and reports no new results; it emphasizes the need for more standardized studies.

This study found that normal murine hair follicles are direct targets for melatonin bioregulation, expressing receptors that are regulated in a hair cycle-dependent manner, influencing keratinocyte apoptosis.