Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that the observed isotropic ss-ECD spectrum of finasteride is influenced by the anisotropy of locally oriented crystals, offering new possibilities for analyzing solid-state chiral materials.

This study demonstrates that spatially resolved IR and Raman imaging can effectively reveal the molecular structure and composition of untreated human hair, providing insights into its chemistry and structural integrity.

This review examines the effects of various factors on the molecular and nanostructural ordering of human hair, highlighting its potential as a diagnostic material for environmental and public health monitoring, but reports no new experimental results.

This study found that mu-crystallin gene expression in mouse skin is highest during the anagen phase of hair development, suggesting its possible role in hair follicle growth.

This review discusses pyrene excimer nucleic acid probes for detecting biomolecules and protein-DNA interactions and reports no new experimental findings.

In this study, researchers investigated the formation of spherical crystals of minoxidil in various alcoholic solvents, discovering new types like spherulite aggregates and a unique butterfly-shaped crystal, with the spherulite aggregates showing improved powder flow properties compared to other forms.

This study utilized a sequence-structure alignment approach to improve the characterization of Class A Rhodopsin GPCR superfamily, including orphan and unclassified receptors, through evolutionary analysis.

Molecular dynamics simulations help understand keratin's properties and predict hair's response to treatments.

This study found that the cocrystal of mycophenolic acid with isonicotinamide significantly improved solubility and dissolution rate, while two other cocrystals showed decreased performance in these areas.

This study utilized magnetic resonance imaging to noninvasively visualize and differentiate skin structures in rat skin, finding a significant correlation between MRI data and histological areas.

This study reported that X-ray microscopy provides more intact images of hair's internal structure compared to transmission electron microscopy, particularly for observing fine details like cuticle coarsening and cortex cracks.

This study observed that the Raman spectra of human hair cuticle vary with polarization and direction of signal collection, identifying certain spectral bands as markers sensitive to the structural changes in keratin secondary and tertiary structures.

This study used advanced analytical techniques to reveal that proteins and lipids are distributed unevenly in hair, with distinct structural differences depending on their location within the fiber.

This study shows that microdiffraction experiments reveal structural layers in keratinous tissues, each with different keratin types, potentially explaining their dual role as mechanical support and chemical barriers.

This study introduced a new computational method for simulating vibrational frequencies, finding that the multi-molecular fragment model showed the best agreement with experimental data for Finasteride, Lamivudine, and Repaglinide, outperforming traditional models in accuracy.

This study comprehensively compared different crystalline forms of finasteride, including the new finasteride DMF solvate hemihydrate, to better understand their structural characteristics and intermolecular interactions.

This study confirms that the proposed universal model for hard α-keratin structure applies to all known forms across various mammalian species.

This article reports electron microscope studies on the structure of hair and wool, but it does not present new clinical findings.

In this study, minoxidil nanoparticles significantly increased hair growth rate in C57BL/6 mice compared to traditional minoxidil, suggesting enhanced effectiveness and potential as a new formulation.

This study developed a non-destructive X-ray fluorescence technique to quantitatively analyze elemental content in human hair and constructed a database of element concentrations in healthy Swedish, Caucasian individuals.

This study discovered a new region in the hair cortex where intermediate filaments are both aligned with the hair's axis and orientationally ordered, influenced by the cuticle boundary.

This study reports the development of a novel protocol to purify human TRPV3 ion channels, revealing functional properties and differences in ligand interactions, enabling further structural and functional research.

This study found that synchrotron radiation ECD imaging provides new insights into solid-state Finasteride by highlighting the significant role of anisotropy in local domains for chiroptical measurements.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

This study found evidence of structurally and functionally distinct AR-SARM protein complexes, which may contribute to understanding how SARMs achieve tissue-selective effects.

This study synthesized and verified the structures of Setipiprant's major and minor metabolites, confirming their regio- and enantioselectivity from earlier proposals in a clinical study.

In this study, researchers developed hollow mesoporous organosilica nanoparticles and confirmed their synthesis using IR spectroscopy, then evaluated the nanoparticles for endocytosis and biocompatibility, although specific results of these tests are not reported in the abstract.