January 2026 in “Journal of Hard Tissue Biology” This study found that red LED photobiomodulation significantly enhanced both the metabolic activity and proliferation of human placenta-derived pericytes, alongside increased expression of angiogenic markers, suggesting a potential non-invasive approach to aid tissue repair and vascular regeneration.
23 citations
,
January 1981 This article reviews the composition and structure of mammalian hard keratins, focusing on the filamentous and nonfilamentous protein content, and reports no new experimental results.
17 citations
,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” The excimer laser may help hair regrow in alopecia areata patients.
14 citations
,
August 2016 in “Journal of nanomedicine research” This animal study found that biscuits fortified with zinc oxide nanoparticles improved growth, appetite, and hair growth in zinc-deficient rats more effectively than traditional zinc forms, without apparent toxicity.
12 citations
,
June 2022 in “International Journal of Molecular Sciences” In this study, copper was found to promote the proliferation of dermal papilla cells in Rex rabbits by maintaining the function of the cellular mitochondrial electron transport chain.
2 citations
,
February 2022 in “Biology” This study found that blue laser irradiation reduced ATP levels and cell viability in mouse skin by increasing oxidative stress through the production of reactive oxygen species.
2 citations
,
May 2014 in “Journal of The American Academy of Dermatology” Melanoma thickness at diagnosis is linked to access to dermatologists and preventive services, not to socioeconomic status.
1 citations
,
July 2017 in “Microscopy and Microanalysis” In this study using C57BL/6 mice, researchers found that iron oxide nanoparticles permeated skin primarily through hair follicles and sebocytes, with absorption increasing over time.
May 2024 in “Brazilian Journal of Hair Health” In this study, both red and blue light phototherapy were found to increase hair density, reduce the central parting, and boost the number of terminal hairs in individuals with Androgenetic Alopecia, over 12 weeks of treatment.
October 2023 in “Microorganisms” This study reported that COVID-19 patients treated with nirmatrelvir/ritonavir had lower anti-spike IgG levels and different cytokine patterns compared to those not receiving antiviral treatment, suggesting early antiviral use may alter immune response by reducing viral load and antigen presentation.
195 citations
,
January 2008 in “Photochemistry and Photobiology” This review discusses the effects of visible light on human skin, highlighting its role in pigmentation, thermal damage, and the treatment of several skin conditions, while noting limited sunscreen protection against it; no new clinical results are reported.
80 citations
,
June 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” This study observed that smaller polymeric submicron particles provided more efficient selective drug delivery to inflamed skin in a mouse model, enhancing therapeutic effects while reducing systemic adverse effects.
23 citations
,
July 2021 in “Life” This review evaluates the potential benefits and mechanisms of blue light therapy for skin conditions like atopic dermatitis and acne, but highlights the need for further research on safety and clinical protocols.
5 citations
,
October 2023 in “International Wound Journal” In this study, a novel portable LED device significantly accelerated wound healing in rats, with faster wound closure, increased collagen deposition, and more microvessels at a higher radiation intensity, suggesting its potential for innovative wound management.
3 citations
,
October 2006 in “Journal of dermatology” This study reported that X-ray microscopy provides more intact images of hair's internal structure compared to transmission electron microscopy, particularly for observing fine details like cuticle coarsening and cortex cracks.
2 citations
,
March 2021 in “Dermatologic Therapy” This study found that low-level laser therapy significantly increased hair counts in women with female pattern hair loss but not in those with telogen effluvium, without serious adverse events.
February 2025 in “Cosmetics” This narrative review explored how blue light therapy may offer therapeutic benefits for various skin disorders by affecting microbial activity and immune responses, promoting hair growth, and aiding skin rejuvenation and healing.
In this study, researchers observed that graded calorie restriction in mice led to changes in stable isotope ratios and elemental content in bone collagen and hair keratin, potentially indicating intensified mobilization of endogenous proteins and altered bone collagen structure with increased dietary stress.
35 citations
,
December 2014 in “Lasers in surgery and medicine” This study found that red light accelerated the transition from the resting to growth phase in hair follicles faster than green and blue light in mice, suggesting it may stimulate hair growth.
33 citations
,
March 2017 in “Dermatologic Surgery” In this clinical study, low-level laser therapy using the HANDI-DOME LASER device increased hair counts by 51% compared to controls, indicating its potential as a safe and effective treatment for androgenetic alopecia in women aged 18 to 60.
27 citations
,
September 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that relatively low concentrations of 1,25(OH)2D3 stimulated human hair follicle and fiber growth, while higher concentrations inhibited growth in a whole-organ culture system.
23 citations
,
September 2011 in “Journal of Dermatological Science” This study explored the effects of a new narrow-band red LED light on hair growth in mice, showing potential benefits compared to existing laser therapies.
20 citations
,
September 2019 in “Nanomaterials” This study developed a portable electrospinning device that mimics hair for cosmetic thickening in a mouse model, showing performance comparable to benchtop models with added safety and cost benefits.
14 citations
,
June 2021 in “Archives of Dermatological Research” In this study, researchers evaluated the use of adipocyte-derived stem cell conditioned media combined with fractional laser or microneedling for treating refractory alopecia areata, finding that 64.3% of patients had significant hair regrowth, suggesting this combination may be an effective and safe treatment option.
9 citations
,
August 2019 in “Journal of the American Academy of Dermatology” Exosomes from stem cells may help treat hair loss.
9 citations
,
August 2017 in “Photochemistry and Photobiology” This study found that isolated red light may serve as an alternative for photo-immunotherapy without additional photosensitizers, as it did not reduce keratinocyte differentiation markers or increase photo-oxidative damage, unlike treatment with IL-4 or UVA1/blue light.
9 citations
,
January 2016 in “Journal of cosmetology & trichology” This article reviews the characteristics and distribution of alopecia areata and reports no new clinical results.
2 citations
,
December 2024 in “Journal of Photochemistry and Photobiology B Biology” This study suggests that pulsed wave photobiomodulation could be a promising treatment for androgenetic alopecia by enhancing dermal papilla cell function through specific light parameters, particularly frequency.
1 citations
,
July 2024 in “Journal of Associated Medical Sciences” This review highlights the mechanisms and therapeutic potential of mesenchymal stem cell-derived exosomes in regenerative medicine and discusses recent advances in their use for treating various ailments, without presenting new clinical findings.
1 citations
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November 2020 in “Journal of Cosmetic Dermatology” This letter to the editor discusses an unusual complication, crescent-shaped incisional cuts, observed with Q-switched Nd:YAG 1064 laser tattoo removal and reports no new clinical results.