Clinical Efficacy of Adipocyte-Derived Stem Cells Conditioned Media Combined with Micro-Injury in Refractory Patch of Alopecia Areata

June 2021 in “ Archives of Dermatological Research ”

Seon Bok Lee, Hyun‐Tae Shin, Ji Won Byun, Jeonghyun Shin, Gwang Seong Choi

adipocyte-derived stem cell conditioned media ASC-CM carbon dioxide fractional laser microneedling alopecia areata stem cell conditioned media fractional laser AA

TLDR Combining stem cell media with laser or microneedling can effectively regrow hair in alopecia areata.

This study evaluated the clinical efficacy and safety of adipocyte-derived stem cell conditioned media (ASC-CM) combined with either a 10,600 nm carbon dioxide fractional laser or microneedling for treating refractory patches of alopecia areata (AA). Conducted retrospectively, it involved 14 patients treated between March 2017 and August 2020. Results showed that 9 out of 14 patients (64.3%) experienced more than 50% hair regrowth, with 6 patients (42.9%) achieving complete recovery. The average time to achieve over 50% hair regrowth in responders was 11.3 weeks. In contrast, 5 patients were non-responders, with 4 showing less than 25% regrowth and 1 showing slight regrowth after 3 months. The study concluded that ASC-CM combined with fractional laser or microneedling could be an effective and safe treatment option for refractory AA patches.

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Research cited in this study

15 / 15 results

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205 citations , April 2013 in “British Journal of Dermatology”

Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.

research Histopathology of Alopecia Areata, Acute and Chronic: Why Is It Important to the Clinician?

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244 citations , January 2010 in “Journal of the American Academy of Dermatology”

The document says current treatments for alopecia areata do not cure or prevent it, and it's hard to judge their effectiveness due to spontaneous remission and lack of studies.

Hair Growth Stimulated by Conditioned Medium of Adipose-Derived Stem Cells Is Enhanced by Hypoxia: Evidence of Increased Growth Factor Secretion

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

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in Research 865 upvotes 1 year ago

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in Chat 11 upvotes 1 year ago

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in Research/Science 99 upvotes 1 year ago

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community The Big Fat Layer II

in Research/Science 26 upvotes 4 years ago

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in Update 114 upvotes 7 years ago

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