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    Glossary Nitrogen Mustard

    chemotherapy drug derived from chemical warfare agents

    Nitrogen Mustard, also known as Mechlorethamine, is a type of chemotherapy drug originally derived from chemical warfare agents. It works by interfering with the DNA of rapidly dividing cells, making it effective in treating certain cancers, such as Hodgkin's lymphoma. However, it can also cause side effects like hair loss (alopecia) due to its impact on healthy rapidly dividing cells, including those in hair follicles.

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    1. Topical nitrogen mustard in the treatment of alopecia areata: a bilateral comparison study Journal of The American Academy of Dermatology · 2003 · 16 citations
    2. MG53 Mitigates Nitrogen Mustard-Induced Skin Injury Cells · 2023 · 3 citations
    3. Nitrogen Mustard Induces DNA Damage and Structural Changes in Mouse Skin Hair Follicles The FASEB Journal · 2015
    4. Determination of cantharidin,nitrogen mustard and minoxidil in nurturing hair products by liquid chromatography-tandem mass spectrometry Huanjing yu Jiankang Zazhi · 2016
    5. Alopecia Areata Archives of dermatology · 1992 · 49 citations
    6. Current management strategies for cutaneous T-cell lymphoma Clinics in Dermatology · 2004 · 39 citations
    7. The treatment of alopecia areata. PubMed · 1987 · 21 citations
    8. Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes Journal of Investigative Dermatology · 2003 · 19 citations
    9. 015 Hypopigmented Mycosis Fungoides Progressing to Systemic Involvement- A Case Report and Review of Literature Journal of Investigative Dermatology Symposium Proceedings · 2017
    10. Alkylating Agents 2013
    11. Dermatologic therapy: December 1984 through December 1985 Journal of the American Academy of Dermatology · 1986
    12. Cutaneous and Ocular Late Complications of Sulfur Mustard in Iranian Veterans Cutaneous and Ocular Toxicology · 2007 · 94 citations
    13. The Expression of P-Responsive Genes is Related to Root Hair Growth The Proceedings of the International Plant Nutrition Colloquium XVI · 2009 · 1 citations
    14. Ethnodermatological use of medicinal plants in India: From ayurvedic formulations to clinical perspectives – A review Journal of ethnopharmacology · 2021 · 57 citations
    15. A Concept on The Development of The DRDE Series of Compounds for Skin Diseases Using In-Silico ADME And Drug-Likeness Analysis Preprints.org · 2026
    16. New Drugs for Leukæmia and Tumours The Lancet · 1961
    17. Establishment of an in vitro hairless guinea pig dermal model PLoS ONE · 2026
    18. Eco-innovation in action: valorizing vegetable waste into high-value ingredients for sustainable applications Frontiers in Sustainable Food Systems · 2025 · 6 citations
    19. Herbal Therapy for the Treatment of Seborrhea Dermatitis Clinical Cosmetic and Investigational Dermatology · 2022 · 21 citations
    20. Antibacterial Potency of an Active Compound from Sansevieria trifasciata Prain: An Integrated In Vitro and In Silico Study Molecules · 2023 · 3 citations
    21. AMINOPTERIN IN TREATMENT OF LEUKEMIA IN CHILDREN American journal of diseases of children · 1950 · 23 citations
    22. Cutaneous complications of chemotherapeutic agents Journal of The American Academy of Dermatology · 1983 · 172 citations
    23. Reversal of Baldness in Patient Receiving Minoxidil for Hypertension The New England Journal of Medicine · 1980 · 95 citations
    24. Role for the Epidermal Growth Factor Receptor in Chemotherapy-Induced Alopecia PLoS ONE · 2013 · 20 citations
    25. REVIEW OF SO-CALLED ASEPTIC NEUTROPHILIC DERMATOSES Australasian Journal of Dermatology · 1983 · 17 citations
    26. Urticaria, Drug Hypersensitivity Rashes, Nodules and Tumors, and Atrophic Diseases Elsevier eBooks · 2012 · 4 citations
    27. Chemotherapy and Cutaneous Drug Reactions Springer eBooks · 2015 · 1 citations
    28. 016 Anesthetics Prior to Keloid Injections: A Painless Approach Journal of Investigative Dermatology Symposium Proceedings · 2017
    29. Index 2013
    30. Contents Dermatologic Clinics · 2010