Hypopigmented Mycosis Fungoides Progressing to Systemic Involvement: A Case Report and Review of Literature
September 2017
in “
Journal of Investigative Dermatology Symposium Proceedings
”
TLDR A 73-year-old woman with Hypopigmented Mycosis Fungoides, a rare skin lymphoma, experienced disease progression despite treatment, emphasizing the need for ongoing monitoring.
The document from 2017 reported a case of a 73-year-old African American female diagnosed with Hypopigmented Mycosis Fungoides (HMF), an uncommon subtype of primary cutaneous T cell lymphoma (CTCL) that typically affects darker skin types and younger populations. The patient was treated with oral PUVA and topical nitrogen mustard since 2000, experiencing periods of remission and recurrence. In 2015, new hypopigmented patches and an erythematous plaque emerged, with a biopsy and serum evaluation confirming the progression of the disease. Despite HMF usually showing slower progression and a good prognosis with a 90% remission rate, the case highlighted the importance of continuous monitoring for disease progression through skin surveillance biopsies and serum evaluations.
