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    Glossary Nitrogen Mustard

    chemotherapy drug derived from chemical warfare agents

    Nitrogen Mustard, also known as Mechlorethamine, is a type of chemotherapy drug originally derived from chemical warfare agents. It works by interfering with the DNA of rapidly dividing cells, making it effective in treating certain cancers, such as Hodgkin's lymphoma. However, it can also cause side effects like hair loss (alopecia) due to its impact on healthy rapidly dividing cells, including those in hair follicles.

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    1. Topical nitrogen mustard in the treatment of alopecia areata: a bilateral comparison study Journal of The American Academy of Dermatology · 2003 · 16 citations
    2. MG53 Mitigates Nitrogen Mustard-Induced Skin Injury Cells · 2023 · 3 citations
    3. Nitrogen Mustard Induces DNA Damage and Structural Changes in Mouse Skin Hair Follicles The FASEB Journal · 2015
    4. Determination of cantharidin,nitrogen mustard and minoxidil in nurturing hair products by liquid chromatography-tandem mass spectrometry Huanjing yu Jiankang Zazhi · 2016
    5. Alopecia Areata Archives of dermatology · 1992 · 49 citations
    6. Current management strategies for cutaneous T-cell lymphoma Clinics in Dermatology · 2004 · 39 citations
    7. The treatment of alopecia areata. PubMed · 1987 · 21 citations
    8. Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes Journal of Investigative Dermatology · 2003 · 19 citations
    9. 015 Hypopigmented Mycosis Fungoides Progressing to Systemic Involvement- A Case Report and Review of Literature Journal of Investigative Dermatology Symposium Proceedings · 2017
    10. Alkylating Agents 2013
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