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      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

    Research

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      community Minoxidil doesn’t work over night.

      in Is this regrowth?  196 upvotes 2 months ago
      Minoxidil requires at least 6 months to show results and may not work for everyone. Combining it with Finasteride can improve outcomes, but stopping Minoxidil can result in losing any regrowth.

      community 5 months of nuking T, 2 months of minoxidil

      in Transgender  489 upvotes 1 year ago
      The user transitioned from finasteride to Cyproterone and started using Minoxidil, resulting in healthier hair and regrowth. They plan to wean off Minoxidil in a year, depending on regrowth.

      community Nandrolone Replacement Therapy

      in Treatment  40 upvotes 2 years ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.
      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 1 week ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.