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Diet changes can protect against harmful environmental effects on fetal development.

Activating the Sonic hedgehog gene in mice can start the hair growth phase.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

ERG increases SOX9, promoting prostate cancer growth and invasion.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

BMAL1 controls skin cell growth and UV damage risk, peaking at night.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Patients with hidradenitis suppurativa have a different skin microbiome compared to healthy people.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Skin fat cells help with skin balance, hair growth, and healing wounds.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

Different small areas within hair follicles send specific signals that control what type of cells stem cells become.

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

Many COVID-19 patients still have symptoms like fatigue and loss of taste or smell a month after diagnosis.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Different types of skin cells play specific roles in development, healing, and cancer.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.