research Role of Autonomic Dysfunction and Relation with Diastolic Dysfunction in Resistant Hypertensives
Autonomic dysfunction is common in hypertensives but may not cause diastolic dysfunction in resistant hypertension.
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research An Underrecognized Adverse Effect of Azithromycin: Agranulocytosis in a 67-Year-Old Man
Azithromycin can rarely cause a severe drop in white blood cells.
research Granulocyte Colony-Stimulating Factor Treatment of Cyclic Neutropenia with Recurrent Oral Aphthae
G-CSF effectively treated a teenager's cyclic neutropenia and reduced her symptoms without adverse effects.
research Proxalutamide Improves Inflammatory, Immunologic, and Thrombogenic Markers in Mild-to-Moderate COVID-19 Males and Females: An Exploratory Analysis of a Randomized, Double-Blinded, Placebo-Controlled Trial Early Antiandrogen Therapy with Proxalutamide
Proxalutamide improved blood markers related to inflammation, immune response, and clotting in COVID-19 patients, potentially reducing hospitalizations.
research Probable Drug-Triggered Pemphigus Foliaceus in a Dog Following Administration of Afoxolaner (NexGard)
A dog developed a skin condition called pemphigus foliaceus after taking NexGard, but got better with treatment.
research Failure of Fresh Plasma in Leiner Disease
Fresh plasma transfusions did not help treat Leiner disease in an infant.
research The Influence of Vitamin C Deficiency on Dermatosis in Neonatal Dairy Calves
Vitamin C deficiency causes severe skin problems in newborn dairy calves.
research Life Sciences Discovery And Technology Highlights
New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
research Editors' Picks
ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.
research Life-Threatening Macrophage Activation Syndrome as the Initial Presentation of Systemic Lupus Erythematosus: A Case Report and Review of the Literature
Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.
research Retiform Purpura Caused by the Use of Cocaine Adulterated with Levamisole
Cocaine possibly mixed with levamisole caused a woman's skin condition and blood issues, which improved with treatment.
research Phenotypic Variability Associated with WNT10A Nonsense Mutations
WNT10A mutations cause varied symptoms in patients with odonto-onycho-dermal dysplasia.
research Bioactivity Guided Isolation and Characterization of the Phytoconstituents from Tridax Procumbens
Tridax procumbens plant parts boost immune response in mice.
research A Case of Primary Cutaneous Natural Killer/T-Cell Lymphoma, Nasal Type, with Indolent Clinical Course: Monoclonal Expansion of Epstein-Barr Virus Genome Correlating with Terminal Aggressive Behavior
The growth of the Epstein-Barr virus in the patient's cells was linked to the worsening of her lymphoma.
research Erythema Nodosum Leprosum: Immunoglobulin G Subclasses and Complement Activation
The study suggests that complement activation, not immunoglobulins, may be important in erythema nodosum leprosum.
research Hair Loss With Rapid Weight Loss
Eating more protein during fast weight loss can prevent hair loss.
research Isomorphic and Isotopic Phenomenon Occurring Simultaneously in a Case of Granuloma Annulare
A patient with granuloma annulare experienced both isotopic and isomorphic responses, with skin lesions responding to steroids but relapsing after stopping treatment.
research Towards a Consensus Potency Assay for Mesenchymal Stromal Cells: A Matrix Analysis of Cell Source, Donor Variability, and Inflammatory Stimuli to Refine Surrogate Markers of Immunomodulation
ATIR101 improves survival in stem cell transplant patients; Australian stem cell treatment decisions are influenced by regulation changes.
research Hazards of Topical Mitotic Blocking Agents
Topical mitotic blocking agents like colchicine can be dangerous and potentially fatal, and hair loss from rapid weight loss is due to low protein, not the speed of weight loss.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Toll-Like Receptor Function in Acute Wounds
Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.
research The Bright Side of Fibroblasts: Molecular Signature and Regenerative Cues in Major Organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Hair Loss During Lithium Treatment
Lithium treatment can cause increased hair shedding and hair loss in patients.
research Feline Superficial Pyoderma: A Retrospective Study of 52 Cases (2001–2011)
Skin infections in cats are more common than thought, often affect young cats with allergies, and need better treatments.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Tofacitinib for the Treatment of Three Immune-Mediated Conditions in One Patient: Ulcerative Colitis, Pyoderma Gangrenosum, and Alopecia Areata
Tofacitinib improved ulcerative colitis, skin ulcers, and hair loss in a patient who didn't respond well to other treatments.
research Successful Combination Therapy of Acne Keloidalis Nuchae
The combination therapy effectively improved acne keloidalis nuchae.
research Latanoprost
A woman got a scalp condition from using latanoprost, but it improved after stopping the drug and starting other treatments.
research Minoxidil
Using minoxidil can cause severe skin reactions in some people.
research Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome
The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.