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Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.

Human prenatal skin develops an immune network early on that helps with skin formation and healing without scarring.

Young C57BL/6 mice heal better than BALB/c mice, and older mice heal faster but regenerate worse.

Collagen XVII is important for skin aging and wound healing.

A woman with a rare autoimmune disorder had a blister on her eye and unique immune reaction, which was effectively treated with medication.

Retinoids and narrowband UVB phototherapy are effective for treating psoriasis and can reduce treatment time when used together.

Psychotropic medications can cause skin problems, including serious conditions, and patients should be monitored closely.

CD201+ fascia progenitors are essential for wound healing and could be targeted for treating skin conditions.

MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Pharmacists should interpret lab data and perform physical exams to improve patient care.

The study suggests that people with rosacea are more likely to have chronic rhinosinusitis.

Activating TRPA1 reduces scarring and promotes tissue regeneration.

Different types of fibroblasts play specific roles in wound healing and cancer, which could help improve treatments.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.