research Androgenetic Alopecia: Update on Etiology
AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.
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research Embryology, Histology, and Physiology of the Hair Follicle
The document explains how hair follicles develop, their structure, and how they grow.
research Toxoplasma Gondii Infection and Testosterone Alteration: A Systematic Review and Meta-Analyses
Toxoplasma gondii infection may increase testosterone levels in males.
research Rps14 Upregulation Promotes Inner Ear Progenitor Proliferation and Hair Cell Regeneration in the Neonatal Mouse Cochlea
Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.
research Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity: Lessons from Alopecia Areata
ILC1-like cells can cause alopecia areata by attacking hair follicles.
research New Intranasal and Injectable Gene Therapy for Healthy Life Extension
Gene therapy in mice increased lifespan and improved health without causing cancer.
research 3D-SeboSkin Model Application in Hidradenitis Suppurativa/Acne Inversa
The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.
research Differential Molecular Signature of Dermal Papilla Cells from Balding and Non-Balding Scalp in 2D, 3D Culture and Co-Culture with Adipose-Derived Stem Cells
Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
research Chemicals and Stem Cells in the Promotion of Regeneration
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
research Responses of Type II Spiral Ganglion Neurites to Stripes of Laminin and Fibronectin
Type II spiral ganglion neurites avoid high concentrations of laminin and fibronectin.
research Hair Biology and Androgenetic Alopecia
Hair loss caused by genetics and hormones; more research needed for treatments.
research Functional Hair Follicle Regeneration
Scientists made working hair follicles using stem cells, helping future hair loss treatments.
research The Role of Integrin AlphaVbeta6 in Impaired Wound Healing and Hair Follicle Regeneration
Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.
research Neurotrophins, Nociceptors, And Pain
Neurotrophins, especially NGF, are crucial for pain development and management.
research Disorders of Excessive Hair Growth in Adolescents
Hirsutism in teen girls is common, usually harmless, but can sometimes signal serious issues and is treatable.
research Exploring the Role of Melanocyte Subpopulations in Vitiligo
A specific group of early-stage melanocytes is reduced in vitiligo-affected skin, which may explain treatment resistance.
research Neurotrophology of the Hair Follicle: Neurotrophins Act as Auto- and Paracrine Growth Factors and Immunomodulators
Neurotrophins are important for hair growth and response to stress.
research Edar Signaling in the Control of Hair Follicle Development
Edar signaling is crucial for proper hair follicle development and function.
research Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells
Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
research New Effects of Caffeine on Corticotropin-Releasing Hormone (CRH)-Induced Stress Along the Intrafollicular Classical Hypothalamic-Pituitary-Adrenal (HPA) Axis (CRH-R1/2, IP3-R, ACTH, MC-R2) and the Neurogenic Non-HPA Axis (Substance P, p75NTR and TrkA) in Ex Vivo Human Male Androgenetic Scalp Hair Follicles
Caffeine may help reduce stress-induced hair loss.
research The Effects of GPR40 Agonists on Hair Growth Are Mediated by ANGPTL4
GPR40 agonists help hair growth through the protein ANGPTL4.
research Role of Platelet and Growth Factor Concentration in Platelet Rich Plasma Therapeutic Response to Alopecia
High platelet numbers in PRP may not be essential for hair growth, and certain growth factors could negatively affect treatment outcomes for hair loss.
research Functional Annotation of Genes Underlying Hair Disorders
The study identified key genes and pathways linked to hair disorders, aiding precision medicine.
research Hair Physiology
Hair grows in three stages: growing, transition, and resting.
research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
research Delta Opioid Receptors Presynaptically Regulate Cutaneous Mechanosensory Neuron Input to the Spinal Cord Dorsal Horn
The study revealed that delta opioid receptors (DOR) played a crucial role in regulating cutaneous mechanosensation, including touch, by inhibiting synaptic input to the spinal dorsal horn through blocking voltage-gated calcium channels. DOR was primarily expressed in large-diameter, myelinated mechanoreceptors, challenging previous beliefs about its expression in small-diameter neurons. The research used a DORGFP knockin mouse model to map DOR distribution and found that DOR agonists like deltorphin II significantly reduced neurotransmitter release, suggesting a potential target for treating injury-induced mechanical hypersensitivity. The study highlighted the distinct roles of DOR and mu opioid receptors (MOR) in somatosensory processing, with DOR affecting mechanoreceptors involved in touch sensation and MOR associated with nociceptive pathways. These findings provided insights into the molecular mechanisms by which opioids could modulate touch and pain sensations.
research Do Hair Bulb Melanocytes Undergo Apoptosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research Dermal Fibroblasts in Cutaneous Development and Healing
Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
research The Structure and Organization of Lanceolate Mechanosensory Complexes at Mouse Hair Follicles
Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
research A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock
BMAL1 and Period1 genes can influence human hair growth.