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The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.

Finasteride helps brain function in rats with liver-related brain issues.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.

Finasteride reduces movement issues in Parkinson's disease rats.

Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.

Finasteride affects young male rats' brain function and behavior negatively.

Early NAS level changes affect alcohol consumption vulnerability.

Finasteride helps protect brain in old male rats.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Some common medications can harm male fertility, but many effects can be reversed.

Early hormones shape sex-specific differences in rat glands.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Consider benefits and risks of new alopecia treatments for safety.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

Letrozole reduces seizures but not brain damage in mice.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.