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Certain gene variations and different levels of BDNF and CRH hormones are linked to vitiligo.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Certain existing drugs, like glycopyrronium and botulinum toxin type A, may help treat excessive sweating.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Cannabinoids may help treat various skin conditions.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

New genetic discoveries may lead to better treatments for alopecia areata.

Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.

Notch signaling is essential for healthy skin and hair follicle maintenance.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Different types of stem cells help maintain and heal skin.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.

Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.

Notch signaling disruptions can cause various skin diseases.

Higher early lead exposure is linked to delayed puberty in girls.

Astressin-B can reverse and prevent hair loss in stressed mice.

Skin problems like acne, excessive hair growth, and oily skin are common in women with PCOS and can help with early diagnosis.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

People with the same genetic mutation for Woodhouse-Sakati syndrome can have different symptoms.

N1-methylspermidine helps hair growth and reduces inflammation in hair follicles.

Modified laparoscopic sleeve gastrectomy effectively controls diabetes and treats obesity with minimal complications.