33 citations,
December 2015 in “Neuroendocrinology” Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
26 citations,
July 1995 in “Neurobiology of Aging” Finasteride affects prostate weights and pituitary activity differently with age.
2 citations,
September 2017 in “Archives of Medical Science” Finasteride affects offspring's antioxidant enzymes in epididymis, possibly disrupting sperm maturation.
March 2021 in “Clin-Alert” The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.
65 citations,
April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
February 2024 in “Brain research bulletin” Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.
49 citations,
March 2018 in “Toxicological sciences” Low doses of mixed chemicals cause permanent reproductive malformations in male rats.
Different drugs are used to manage breeding, prevent or end pregnancy, and treat reproductive issues in dogs and cats.
157 citations,
May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
111 citations,
March 2012 in “Expert Opinion on Drug Delivery” Liposomes could improve how skin care products work but are costly and not very stable.
39 citations,
January 2019 in “Journal of Dermatological Treatment” Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.
22 citations,
August 2017 in “Stem cells and cloning” Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.
September 2023 in “Journal of microbiology and biotechnology” A type of collagen helps hair grow by boosting cell growth and activating a specific hair growth pathway.
October 2022 in “Biomolecules” Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.
86 citations,
July 2020 in “International Journal of Molecular Sciences” Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
82 citations,
August 2006 in “Pharmacology, Biochemistry and Behavior” Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.
51 citations,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Certain drugs that block specific enzymes can help treat prostate diseases.
31 citations,
September 2008 in “International Journal of Andrology” 5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
28 citations,
May 2015 in “Addiction Biology” Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
18 citations,
November 2014 in “Journal of Agricultural and Food Chemistry” Brazilian propolis was found to speed up hair growth in mice by increasing the growth of skin cells that form hair.
17 citations,
February 2019 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
13 citations,
January 2020 in “Neuroscience” Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
3 citations,
June 2006 in “Expert Review of Dermatology” The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
January 2012 in “Elsevier eBooks” New treatments for skin and hair repair show promise, but further improvements are needed.
7 citations,
January 2018 in “Reproduction” Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
305 citations,
February 2007 in “Hormone and metabolic research” Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
February 2024 in “Cosmoderma” Low-dose oral minoxidil can help treat male and female pattern hair loss, especially in those who can't use topical treatments or have heart health issues.
61 citations,
June 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
November 2023 in “Materials Today Bio” Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.