research Hedgehog Stimulates Hair Follicle Neogenesis by Creating Inductive Dermis During Murine Skin Wound Healing
The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
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570-600 / 1000+ results research Wounding Induces Dedifferentiation of Epidermal Gata6+ Cells and Acquisition of Stem Cell Properties
Wounded skin cells can revert to stem cells and help heal.
research Molecular Mechanisms of Viral Oncogenesis in Humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research Regenerating the Skin: A Task for the Heterogeneous Stem Cell Pool and Surrounding Niche
Different types of stem cells and their environments are key to skin repair and maintenance.
research Localized In Vivo Genotypic and Phenotypic Correction of the Albino Mutation in Skin by RNA-DNA Oligonucleotide
research Efficient Delivery of Transgenes to Human Hair Follicle Progenitor Cells Using Topical Lipoplex
research Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF
Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
research Microenvironmental Reprogramming of Thymic Epithelial Cells to Skin Multipotent Stem Cells
Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
research Dental Cell Type Atlas Reveals Stem and Differentiated Cell Types in Mouse and Human Teeth
The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
research A PAX1 Enhancer Locus Is Associated With Susceptibility to Idiopathic Scoliosis in Females
A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.
research Generation of Folliculogenic Human Epithelial Stem Cells from Induced Pluripotent Stem Cells
Scientists created stem cells that can grow hair and skin.
research Tissue Regenerative Delays and Synthetic Lethality in Adult Mice After Combined Deletion of ATR and TRP53
Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research Olfactory Receptor OR2AT4 Regulates Human Hair Growth
A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.
research Ferreting Out Stem Cells From Their Niches
New methods have greatly improved our understanding of stem cell behavior and roles in the body.
research Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence
Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
research Mechanisms of Disease: Selective Inhibition of 11β-Hydroxysteroid Dehydrogenase Type 1 as a Novel Treatment for Metabolic Syndrome
Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
research Meta-Analysis Identifies Novel Risk Loci and Yields Systematic Insights into the Biology of Male-Pattern Baldness
Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.
research Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness
Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.
research New Hair From Healing Wounds
Adult mice can grow new hair from skin wounds.
research GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk
Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
research Stem Cell Plasticity Enables Hair Regeneration Following Lgr5+ Cell Loss
Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
research Tcf3 Promotes Cell Migration and Wound Repair Through Regulation of Lipocalin 2
Tcf3 helps cells move and heal wounds by controlling lipocalin 2.
research Inhibiting Janus Kinases to Treat Alopecia Areata
JAK inhibitors might help treat alopecia areata.
research Spontaneous Tumor Regression in Keratoacanthomas Is Driven by Wnt/Retinoic Acid Signaling Cross-Talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Noncoding dsRNA Induces Retinoic Acid Synthesis to Stimulate Hair Follicle Regeneration via TLR3
Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.
research Promotion of Homology-Directed DNA Repair by Polyamines
Polyamines help fix DNA damage accurately in cells.
research Regulation of Masculinization: Androgen Signaling for External Genitalia Development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.