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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Men with low testosterone should be carefully evaluated and monitored before and during treatment.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Hair analysis can somewhat track past testosterone levels but is influenced by factors like hair washing, growth rate, sex, and hair color.

Segmental hair analysis can track testosterone over time but needs adjustments for sex, hair color, and washing frequency.

Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.

Low ferritin and Vitamin D levels may cause hair loss after COVID-19.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Cosmetic hair treatments can increase hair testosterone levels, while natural hair color does not affect it.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

The method shows hair testosterone levels reflect those in saliva, but are affected by various factors and may indicate a risk for heart attack.

Plant-based treatments might help with hair loss and have fewer side effects than synthetic drugs.

Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.

Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.

Honokiol might help reduce male skin aging by maintaining testosterone levels.