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Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Men with low testosterone should be carefully evaluated and monitored before and during treatment.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Hair analysis can somewhat track past testosterone levels but is influenced by factors like hair washing, growth rate, sex, and hair color.

Segmental hair analysis can track testosterone over time but needs adjustments for sex, hair color, and washing frequency.

Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Some sports supplements can cause health issues like mood swings, hair loss, and heart problems in men.

Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.

Low ferritin and Vitamin D levels may cause hair loss after COVID-19.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

The method shows hair testosterone levels reflect those in saliva, but are affected by various factors and may indicate a risk for heart attack.

Citrullus colocynthis fruit extract may effectively treat testosterone-related hair loss, similar to finasteride.

Natural extracts like peppermint and rosemary oils are effective for hair growth and scalp health.

Plant-based treatments might help with hair loss and have fewer side effects than synthetic drugs.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.