research Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-Analysis
Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
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research Polycystic Ovary Syndrome: Comprehensive Overview
PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.
research Targets to Treat Androgen Excess in Polycystic Ovary Syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research TLR9 Activation in Large Wound Induces Tissue Repair and Hair Follicle Regeneration via γδT Cells
Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
research Sexual Dysfunction, Including Hypoactive Sexual Desire Disorder: Diagnosis and Treatment Recommendations
Testosterone therapy can improve sexual function in women but long-term safety is unclear.
research Dehydroepiandrosterone for Women in the Peri- or Postmenopausal Phase
DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.
research Androgen Treatment in Women
Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.
research Promotion of Hair Growth by Rosmarinus Officinalis Leaf Extract
Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
research Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib
A patient with Alopecia Areata had complete hair regrowth after using the drug baricitinib.
research Effects of Baicalin on Alopecia and the Associated Mechanism
Baicalin may help treat hair loss by promoting hair follicle growth and activating specific cellular pathways.
research Multiple-Wavelength Radiation Promotes Hair Growth by Enhancing the Early Stages of Hair Follicle Development in Human Dermal Papilla Cells and C57BL/6 Mice
Multiple-wavelength radiation helps hair grow by boosting early hair follicle development.
research Stimulation by Exosomes from Hypoxia-Preconditioned Hair Follicle Mesenchymal Stem Cells Facilitates Mitophagy by Inhibiting the PI3K/AKT/mTOR Signaling Pathway to Alleviate Ulcerative Colitis
Exosomes from special stem cells help treat ulcerative colitis by reducing inflammation and stress.
research Androgenetic Alopecia: An Update Of Treatment Options
Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.
research Scientific Opinion on the Tolerable Upper Intake Level for Selenium
Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.
research MiR-29 Is an Important Driver of Aging-Related Phenotypes
miR-29 is a key factor that accelerates aging.
research Surrogate End-Points or Primary Outcomes in Clinical Trials in Women with Polycystic Ovary Syndrome?
The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
research A Machine Learning and Network Framework to Discover New Indications for Small Molecules
A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.
research Stem Cell Therapies in Basic Science and Translational Medicine: Current Status and Treatment Monitoring Strategies
Stem cell therapies show promise for treating various diseases but face challenges in clinical use and require better monitoring techniques.
research Alternative Medicine for Hair Loss
Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.
research Androgen Excess: Investigations and Management
The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.
research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report
The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
research GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk
Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
research DPP-4 Inhibition with Linagliptin Ameliorates the Progression of Premature Aging in Klotho−/− Mice
Linagliptin slows down premature aging in certain mice.
research Interventions for Nail Psoriasis
Some systemic treatments work for nail psoriasis but can have serious side effects.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Endocrine Therapy-Induced Alopecia in Patients With Breast Cancer
Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.
research Biallelic HEPHL1 Variants Impair Ferroxidase Activity and Cause an Abnormal Hair Phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
research A PAX1 Enhancer Locus Is Associated With Susceptibility to Idiopathic Scoliosis in Females
A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.
research Thiosulfate Promotes Hair Growth in Mouse Model
Thiosulfate may help hair grow faster in mice and works well with a common hair growth treatment.
research Finasteride
Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.