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Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Keratin films from human hair can potentially replace human nail plates for drug testing.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Chemotherapy often causes hair loss, nail changes, and mouth issues, but these are usually manageable.

Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.

There are two types of stem cells in rodent hair follicles, each with different keratin proteins.

Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.

Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.

Diagnosing hair loss disorders needs clinical, dermoscopic, and histological differences, and checking menstrual cycle, weight changes, drug therapy, and nail changes.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Elkonyxis, a rare nail condition, improved when patients stopped their nail-picking habits.

Early diagnosis and treatment of nail and skin conditions can improve health and appearance.

The document concludes that skin and nail changes can indicate various underlying health conditions.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Immune cells are crucial for hair growth and preventing hair loss.

Immune cells are essential for early hair and skin development and healing.

Many patients with cutaneous lupus erythematosus experience hair loss and nail problems, which are important for diagnosis and treatment.

Darier-White disease causes skin and nail issues, starts around age 20, worsens until 40-50, and has poor treatment options.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

Taking choline-stabilized orthosilicic acid orally significantly improved hair, skin, and nail health without side effects.

Reflectance confocal microscopy can noninvasively diagnose onychomatricoma by showing unique features different from healthy nails or nail fungus.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.

Boosting β-catenin signaling in certain skin cells can enhance hair growth.

Keratoacanthoma comes from hair follicle cells.

Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.

Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.