research Alopecia and the Metabolic Syndrome
Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
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research Clinical Development of Topoisomerase-Interactive Drugs
New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
research 5α-Reductase Inhibitors: The Finasteride Story
Finasteride safely treats enlarged prostate and male-pattern baldness.
research Hdac1 and Hdac2 Regulate the Quiescent State and Survival of Hair-Follicle Mesenchymal Niche
Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
research Viewpoint 3
Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
research Chemical Composition and Biological Activities of Essential Oils of Curcuma Species
Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.
research Comparison of N-Acetyl Cysteine with Metformin on Clinical Profile in Anovulatory Infertile Women with PCOS
N-acetyl cysteine and metformin both improved fertility in women with PCOS equally, but N-acetyl cysteine had fewer side effects.
research The PPAR-γ Modulator, N-Acetyl-GED, Protects From Epithelial-Mesenchymal Transition in Human Hair Follicles: Potential Relevance for Scarring Alopecia
N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.
research TRAIL Sensitization of PC3 Prostate Cancer Cells by Doxorubicin Can Be Blocked by the Antioxidant N-Acetyl-Cysteine or by the Iron Chelator Deferoxamine
Antioxidants can block the cancer-fighting effects of doxorubicin.
research Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of Early-Onset Androgenetic Alopecia in Men
N-acetyl-cysteine improves hair growth and is safe for treating early male hair loss.
research Evidence of Hair Loss After Subacute Exposure to 2-Chloroethyl Ethyl Sulfide, a Mustard Analog, and Beneficial Effects of N-Acetylcysteine
Mustard gas exposure causes hair loss, but treating with N-acetylcysteine can prevent it.
research Induction of Transforming Growth Factor-Beta 1 by Androgen Is Mediated by Reactive Oxygen Species in Hair Follicle Dermal Papilla Cells
Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
research Peroxisome Proliferator-Activated Receptor-γ Signalling Protects Hair Follicle Stem Cells from Chemotherapy-Induced Apoptosis and Epithelial-Mesenchymal Transition
Activating PPAR-γ signalling can protect hair follicle stem cells from damage caused by chemotherapy.
research Simultaneous LC-MS/MS Quantification of Glucocorticoids, Melatonin, and Its Metabolites in Hair
The new method can measure sleep-related hormones in hair effectively and could help track long-term sleep patterns.
research Monilethrix: A Rare Inherited Hair Shaft Disorder in Siblings
Monilethrix is a genetic hair disorder causing fragile, beaded hair with no effective treatment.
research Monilethrix: A Rare Hereditary Condition
Monilethrix is a rare genetic hair disorder that's hard to treat.
research A Case of Trichotillomania Presenting as a Factitious Ulcer
Thorough patient interviews are crucial to identify self-inflicted hair loss.
research N-Acetylcysteine in the Treatment of Trichotillomania
N-acetylcysteine may help treat trichotillomania.
research Development and Characterization of Polydeoxyribonucleotide Loaded Chitosan Polyplex for Wound Healing
The chitosan/PDRN polyplex improved wound healing in diabetic rats.
research Highlights
Melatonin may help with nerve pain, a hepatitis C drug is effective but has side effects, a treatment for mouth sores works but can cause blood issues, ear reconstruction with an implant is safe, HIV transmission from mother to child in Taiwan is now 0% with treatment, certain blood problems are more common in people with a tongue condition, a gene and being overweight are linked to hair loss in some women, a new technique could reduce radiation for lung nodule patients, a hepatitis treatment may lower cancer recurrence after a procedure, and adding extra screening improves tuberculosis detection in patients with lung infections.
research CRISPR/Cas9-Based Targeted Genome Editing for Correction of Recessive Dystrophic Epidermolysis Bullosa Using iPS Cells
The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.
research Different Polyamine Levels in the Vertex and Occipital Hair of Pattern Hair Loss Patients
People with pattern hair loss have higher polyamine levels in the top of their head compared to the back.
research Specialized Ribosomes in Human Dermal Fibroblast Senescence
Specialized ribosomes affect aging in human skin cells.
research Female Hair Loss: Assessment, Categorization, and Management
The document concludes that diagnosing female hair loss requires careful examination, with treatments varying by condition and psychological support often necessary.
research Polycystic Ovary Syndrome (PCOS) – An Overview
PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.
research Boosting Hair Growth Through Follicular Delivery of Melatonin Through Lecithin-Enhanced Pickering Emulsion Stabilized by Chitosan-Dextran Nanoparticles in Testosterone Induced Androgenic Alopecia Rat Model
Melatonin in a special emulsion can help treat hair loss more effectively.
research Hair Loss and 5-Aminosalicylic Acid Enemas
5-aminosalicylic acid enemas may cause hair loss.
research Hair Growth-Promoting Effects of Sargassum Glaucescens Oligosaccharides Extracts
Extracts from a type of brown seaweed can help promote hair growth.
research Melatonin Increases Growth Properties in Human Dermal Papilla Spheroids by Activating AKT/GSK3β/β-Catenin Signaling Pathway
Melatonin may help hair growth by affecting cell growth and hair-related signaling pathways.
research Prostaglandin D2-Enhanced Testosterone Metabolism in Human Keratinocytes Is Mediated by Reactive Oxygen Species
Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.