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This article reviews the genetic basis, diagnostic approaches, and treatment options for nude severe combined immunodeficiency, but does not present any new research findings.

This study developed a new finasteride release system using chitosan-based nanoniosomes, observing that 70% of the drug was released over ten days in vitro, suggesting potential for prostate cancer prevention.

Nephronectin is linked to worse outcomes in breast cancer and helps cancer spread.

This study found that the catalytically inactive serine protease CAP1/Prss8 can still induce skin disorders in mice and is subject to inhibition by nexin-1, independent of its catalytic activity.

This case report describes the diagnosis of Netherton's syndrome in two young sisters, attributing their serious erythrodermia, poor hair growth, and atopic conditions to this hereditary condition.

This review discusses multisystem inflammatory syndrome in adults (MIS-A) related to SARS-CoV2 and outlines the existing knowledge and unanswered questions, reporting no new clinical results.

The study found that hybrid nanoparticles incorporating exosomes with cationic liposomes 2X3-DOPE significantly improved the delivery of both messenger RNA and small interfering RNA to rat cardiac mesenchymal stem cells in vitro, achieving up to 100% transfection efficiency for small interfering RNA.

In this study, researchers found that a specific genetic variant in the INSR gene is linked to severe insulin resistance and hyperandrogenemia in type A insulin resistance syndrome, suggesting the benefit of exon sequencing for accurate diagnosis and treatment.

This case report describes a 9-year-old Korean boy with a calcified nodule on his earlobe, confirmed by histopathologic examination and Von Kossa staining.

This study found a significant association between the IRS-2 gene variant and an increased risk of PCOS, especially in non-obese women in the Chinese population from Taiwan.

This report describes a novel AR gene mutation in a female patient, contributing to androgen insensitivity syndrome, and emphasizes its potential impact on genetic counseling.

In this study, researchers developed a new Supported Ionic Liquid Phase palladium catalyst that showed effectiveness in aminocarbonylation reactions for synthesizing pharmaceutical compounds like CX-546 and a precursor of Finasteride, though results were sensitive to substrate variations and prompted palladium leaching concerns.

A 7-year-old girl was diagnosed with Netherton's Syndrome, shown by skin and hair symptoms.

This study suggests that Foxn1 expression in keratinocytes influences pigmentation in mice, highlighting differences in the molecular mechanisms between mouse and human pigmentation processes.

This study found that a newly created biomimetic microneedle platform effectively expedited wound repair in diabetic animal models by reducing inflammation, enhancing angiogenesis, and promoting skin regeneration through targeted drug delivery and immune response modification.

This article reviews the regulation and roles of spermidine/spermine-N(1)-acetyltransferase (SSAT) in polyamine metabolism and its potential as a target in cancer and other diseases, without reporting new experimental results.

This study describes various clinical phenotypes associated with FOXN1 mutations, finding that affected individuals may develop different severities of immunodeficiency based on their genetic mutations.

In this study, researchers in Southeastern Wisconsin characterized circulating SARS-CoV-2 lineages, notably identifying the dominance of Omicron variants, including sublineages XBB.1.5, XBB.1.16, and XBB.1.9.1, which exhibit mutations aiding viral transmission and immune evasion. This genetic analysis supports public health efforts in monitoring evolving virus strains.

This review discusses the role of the Slug transcription factor in various epidermal functions and its distinction from the related Snail factor, without presenting new research findings.

A new microneedle system may improve hair loss treatment by delivering ketoconazole directly to hair follicles.

This study found that the RapidHIT™ ID system can successfully obtain DNA profiles from single hair roots, particularly those with high nuclei counts.

In this study, researchers identified a novel STS gene (c.287G > A; p.W96*) mutation in Pakistani individuals with X-linked ichthyosis, expanding the understanding of its genetic causes and aiding in genetic counseling.

This study found IL-17/IL-36 signaling to be predominant in both endotypes of Netherton syndrome, with distinct molecular profiles between NS-ILC and NS-SE lesions, offering potential therapeutic targets.

This study found that PEGylated Ag₂S-ZnS@TGA-AA heteronanostructures, activated by light exposure, showed synergistic antibacterial effects against multidrug-resistant bacteria, significantly accelerating the healing of MRSA-infected wounds in comparison to untreated wounds.

This study suggests that using nanostructured lipid carriers may improve the targeting of 17-α-estradiol in treating alopecia by improving skin penetration and stability.

This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.

This study found that incorporating acrylic and methacrylic acid into poly(N-vinyl-2-pyrrolidone) copolymers improves film mechanical properties but negatively affects their interaction with keratin for hair care applications.

This study found that melatonin-mediated lncRNA018392 accelerated cell proliferation and inhibited apoptosis in cashmere goat skin fibroblasts by upregulating the expression of the nearby gene CSF1R.

This phase 2a trial evaluated Samcyprone for common wart treatment and found that while a sensitization reaction is necessary for therapeutic response, its level does not predict wart clearance.

In this study, researchers synthesized nine new nicotinamide derivative compounds and found that one, identified as N4, exhibited significant cytotoxic effects on MCF-7 breast cancer cells, while other derivatives demonstrated notable antibacterial, antifungal, and antibiofilm activities.