This study used proteomic profiling to reveal significant individual and site-specific differences in human hair shaft proteins, which may improve the differentiation of hair based on ethnic origin and individual identity.
January 2026 in “Frontiers in Molecular Biosciences” This study identified a four-gene loop as a non-invasive biomarker that selectively activates in alopecia areata, providing a precise target for JAK inhibitor treatments.
December 2022 in “theses.fr (ABES)” This study found that microplastics on the Lebanese Mediterranean coast transport various organic and inorganic pollutants, posing threats to marine organisms and potentially human health.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that topical Vorinostat induced significant hair regrowth in mice with alopecia areata, suggesting it as a potential repurposable treatment for the condition.
20 citations
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June 2014 in “BMC genomics” This study identified the placenta at the base of the ovary as the origin of poplar seed hair development and detailed transcriptome dynamics during the growth process.
6 citations
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March 2021 in “International Journal of Pharmaceutics” This study reported that a subcutaneous injection formulation using PLGA microspheres to release finasteride stably achieved sustained monthly drug delivery without burst release in beagle dogs, with a dose of 16.8 mg identified as optimal for potential first-in-human trials.
1 citations
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October 2025 in “Scientific Reports” This study investigated the Mandarin duck as a model for understanding lifelong developmental changes, finding that male sail feather morphogenesis involves a combination of local morphogenetic programs, epigenetic regulation, and hormonal cues, with increased female estrogen levels observed before the mating season.
This study reports that hair samples can be used to track chronic hormone levels, revealing stress, reproductive, and sodium regulation patterns in wildebeest related to environmental factors.
May 2018 in “White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)” In this study, researchers found that alopecia areata patients show a significant reduction in suppressive regulatory T-cells and an increase in inflammatory T-cell populations, suggesting an immunological imbalance contributing to the disease.
12 citations
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January 2021 in “Drugs in R&D” This review and meta-analysis found that isotretinoin is an effective treatment for dissecting cellulitis of the scalp, with a high estimated efficacy rate of 90%, yet 24% of patients experienced recurrence after successful treatment.
February 2024 in “International Journal For Multidisciplinary Research” This review examines the advances in nanostructured lipid carriers for treating hyperpigmentation but presents no new clinical results; the authors highlight their potential benefits and applications.
January 2024 in “Wiadomości Lekarskie” This study outlines new strategies for overcoming "cold" tumors, which are typically unresponsive to cancer immunotherapy, with approaches like dendritic cell-based treatments and local immune microenvironment modification, bolstered by both preclinical and clinical trial data.
March 2017 in “Fundamental & Clinical Pharmacology” This case study reported an improvement in lower limb edema for a patient with type 2 diabetes mellitus after starting dulaglutide treatment, suggesting a potential role of the drug in sodium retention disorders.
12 citations
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August 2012 in “ISRN Analytical Chemistry (Print)” This review discusses various chemical and instrumental methods for determining macrolides and reports no new experimental results.
6 citations
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March 2018 in “Journal of Chromatography A” This study describes an analytical technique combining field-enhanced sample stacking with dispersive liquid-liquid microextraction, offering improved sensitivity for detecting finasteride and its metabolite in urine samples from patients treated for androgenetic alopecia.
February 2026 in “International Journal of Advanced Research in Science Communication and Technology” In this review, researchers explored the potential of herbal shampoos as effective and safe alternatives to conventional anti-dandruff treatments, highlighting that polyherbal formulations may offer comparable or superior benefits with fewer side effects.
October 2025 in “Animal Bioscience” This review summarizes the application of genome wide association studies and selection signature analyses in sheep and goat breeding in China, highlighting genomic regions that influence traits like reproductive performance and body size.
211 citations
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February 2009 in “European journal of pharmaceutics and biopharmaceutics” This review summarizes recent advancements in follicular targeting for drug delivery via hair follicles and calls for pilot studies in humans to explore potential clinical applications.
88 citations
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August 2019 in “Nature communications” In this study, researchers identified a specific T cell receptor associated with carbamazepine-induced severe cutaneous adverse reactions, demonstrating its potential for therapeutic development in patients with the HLA-B*15:02 genotype.
33 citations
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January 2017 in “Conservation physiology” This study found that measuring reproductive hormone levels in brown bear hair may effectively support non-invasive genetic sampling, though larger samples or more sensitive techniques are needed for broader application.
31 citations
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May 2019 in “Nature communications” This study found that Blimp1+ cells from mice can generate sebaceous gland organoids in vitro, which mimic natural gland traits and may aid in studying acne vulgaris.
18 citations
,
July 2014 in “Molecular Medicine Reports” This study found that UVB radiation significantly alters miRNA expression and induces cytotoxicity and apoptosis in normal human dermal papilla cells.
6 citations
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May 2020 in “Pharmacology Research & Perspectives” This study in rats found that a new hydroxypropyl-β-cyclodextrin formulation of minoxidil reduced the adverse cardiovascular and proliferative effects seen with traditional minoxidil solutions.
5 citations
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May 2023 in “European Journal of Human Genetics” This study found that mutations in the TULP3 gene are associated with progressive degeneration of the liver, kidney, and heart in adults, highlighting the importance of early detection and management.
2 citations
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January 2019 in “Elsevier eBooks” This review discusses biotin's role in nutrition and suggests no benefit to supplementing it for hair, nails, and skin in healthy individuals; it reports preliminary findings that high dosages may help some multiple sclerosis patients.
1 citations
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January 2021 In this study, CD4+ non-haematopoietic, skin-resident stem cell-like populations were identified in both murine and human epidermis, suggesting they may serve as potential basal cell carcinoma precursors.
June 2026 in “Frontiers in Materials” This review examines advancements in "smart" hydrogel dressings for complex wound healing, highlighting innovations in materials that provide multifunctionality, such as responsive drug delivery and regenerative capabilities. The study also addresses potential challenges in clinical application, like manufacturing and regulatory hurdles.
January 2026 in “Dermatology Practical & Conceptual” This systematic review found that exosome-based therapies significantly improve skin elasticity, reduce wrinkle depth, enhance hydration, and modulate pigmentation, with minimal adverse events reported across multiple studies. However, further clinical trials are necessary to confirm long-term efficacy and safety.
December 2025 in “International Journal of Pharmacology” This review highlights that iPSC-derived artificial platelets offer a promising alternative to platelet-rich plasma for regenerative medicine, with standardized manufacturing and reproducible pharmacological properties, addressing variability issues associated with donor-derived platelets and showing therapeutic potential in preclinical models of osteoarthritis.
December 2025 in “Drug Discovery and Molecular Docking (DDMD)” This review highlights how single-cell transcriptomics has advanced understanding of tissue regeneration by revealing cellular diversity and key molecular interactions in animal models, despite methodological challenges, suggesting future applications in developing targeted regenerative therapies.