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The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Cathepsin L is essential for normal hair growth and development.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Eclipta alba extract helps hair grow faster and more effectively than minoxidil in rats.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

A wearable device using electric stimulation can significantly improve hair growth.

Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Women with PCOS are more likely to suffer from depression, anxiety, and stress.