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The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Understanding where cancer cells come from helps create better prevention and treatment methods.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

Low-level laser therapy, now called photobiomodulation, is recognized for its broad medical applications and scientific backing.

HairMax LaserComb® effectively promotes hair growth and stops hair loss in males with androgenetic alopecia, with no serious side effects.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.