20 citations
,
January 2021 in “GeroScience” This study found that administering spermidine to aged mice for six months significantly reduced various age-related conditions, including brain, heart, kidney, liver issues, and hair loss, possibly due to decreased telomere attrition.
19 citations
,
May 2019 in “JAMA dermatology” This study found that patients with alopecia areata had an increased risk of mortality from self-harm, psychiatric diseases, and lung cancer compared to the general population.
14 citations
,
January 2008 in “Gene therapy” Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.
4 citations
,
July 2022 in “International Journal of Health Sciences” This review discusses rosemary's potential health benefits, including improved scalp circulation and skin protection, but reports no new clinical findings and highlights the need for better regulation and safety data on herbal medicines.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that neonatal Regulatory T cells are crucial for maintaining PPARγ signaling in hair follicles, which supports melanocyte stem cell function and skin pigmentation during early postnatal development.
Vitamin D is crucial for skin health and managing skin diseases.
November 2017 in “Asian journal of pharmaceutical and clinical research” This study predicted that 6-hydroxy genistein, coreximine, and scoulerine from Dadap leaves may act as anti-alopecia agents by interacting with JAK2, but further in-vivo testing is needed.
42 citations
,
October 2012 in “Dermatologic Clinics” This article reviews the use of trichoscopy for diagnosing common hair and scalp diseases and introduces a new classification for specific skin surface abnormalities, without presenting new clinical results.
29 citations
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January 2017 in “Skin appendage disorders” This case study highlights the importance of considering syphilis in the differential diagnosis for hair loss, as patients with the infection may present with non-typical alopecia patterns.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study constructed a comprehensive atlas of prenatal human skin, revealing that innate immune cells, such as macrophages, play a crucial role in skin morphogenesis by interacting with non-immune cells, influencing hair follicle formation and angiogenesis beyond their traditional immune functions.
14 citations
,
April 2020 in “Journal of Cosmetic Dermatology” In this study, intradermal injections of QR678 were found to significantly reduce hair fall in men with androgenetic alopecia over 6 months, with superior improvements in hair density and thickness compared to PRP.
27 citations
,
October 1999 in “Experimental and Molecular Pathology” This article reviews potential animal models for studying androgenetic alopecia and reports no new experimental results; the authors highlight the need for further development of rodent models.
22 citations
,
January 2013 in “International Journal of Trichology” Hair loss is often linked to thyroid problems, especially in women and older people, and screening for thyroid issues is advised for those with hair loss.
15 citations
,
October 2017 in “Journal of Cosmetic and Laser Therapy” This review identifies FDA-cleared home-use photobiomodulation devices for androgenetic alopecia treatment and highlights their excellent safety profile but notes the lack of long-term comparative studies.
14 citations
,
October 2018 in “PloS one” In this study, Far2-/- mice were observed to develop focal alopecia with altered sebaceous gland morphology and lower skin lipid levels compared to wildtype mice.
3 citations
,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified loss of function variants in the HR gene as likely causes of the distinct roaning hair coat seen in lykoi cats.
2 citations
,
October 2000 This report discusses a request for a health hazard evaluation at Equifax in St. Petersburg, Florida concerning potential workplace exposures related to reported employee health issues, particularly hair loss, but provides no new results.
1 citations
,
November 2023 This study examined the prevalence and management of PCOD, finding that it primarily affects unmarried women aged 18-25, causing symptoms like irregular periods and infertility, with many opting for medication and lifestyle changes despite mixed beliefs about their effectiveness.
July 2026 in “International Journal of Drug Delivery Technology” This research reported that liposomal systems made from pig-derived skin lipids enhanced finasteride delivery to hair follicles for treating androgenetic alopecia, showing improved drug deposition, hair length, and growth compared to conventional finasteride forms in vitro.
January 2024 in “Wiadomości Lekarskie” This presentation discusses the importance of fluid therapy in critical care, reviewing current data, guidelines, and emerging technologies to help clinicians make informed decisions about fluid type and volume for treating critically ill patients. Results are not reported in this abstract.
December 2023 in “EPRA international journal of multidisciplinary research” In this review, researchers examined current knowledge on alopecia areata, finding it affects approximately 2% of individuals, with a likely autoimmune and genetic basis, and highlighting its association with other medical and psychiatric conditions, although no cure currently exists.
January 2013 in “Elsevier eBooks” This review discusses spatial and temporal patterns in animals, focusing on skin appendage organs, but provides no new research findings.
April 2024 in “JMIR infodemiology” This study found that TikTok provides valuable insights into experiences with lupus erythematosus, highlighting distress from symptoms, negative perceptions of pharmacologic treatments, and issues with feeling "medically gaslighted.
This study used TikTok videos to explore experiences of individuals with lupus erythematosus, revealing that mucocutaneous symptoms significantly impact mental health and body image, while pharmacologic treatments are often viewed negatively, leading to important implications for clinical interactions and validation.
247 citations
,
August 2011 in “European Journal of Epidemiology” This article outlines the rationale, design, major findings, and updated objectives of the ongoing Rotterdam Study, without presenting new research data.
245 citations
,
January 2018 in “Bone Research” This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.
125 citations
,
September 2019 in “Journal of Clinical Immunology” This review summarizes recent advances in Treg cell biology, focusing on Foxp3's role in immune regulation and therapeutic reprogramming for immune dysregulatory disorders, but reports no new clinical results.
26 citations
,
December 2011 in “Journal of Investigative Dermatology” This review discusses major advances in understanding inherited hair diseases through genetic research and reports no new clinical results; the authors emphasize the potential for new preventive and therapeutic tools.
25 citations
,
September 2013 in “Journal of thoracic oncology” In this animal study, soy isoflavones were found to protect lung tissue from the adverse effects of radiation, such as skin injury, inflammation, and fibrosis, suggesting a potential radioprotective benefit.
22 citations
,
November 2011 in “Journal of Analytical Toxicology” This review discusses the relevance of human androgen receptor action in sports doping and examines the potential of cell-based biological assays for detecting androgenic anabolic steroid use, without presenting new research findings.