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      Early Inductive Events in Ectodermal Appendage Morphogenesis

      research Early inductive events in ectodermal appendage morphogenesis

      160 citations , January 2014 in “Seminars in cell & developmental biology”
      This review discusses the shared molecular and cellular processes in the early development stages of skin appendages like hair follicles, teeth, and mammary glands, reporting no new results.
      Molecular Biology of Hair Morphogenesis: Development and Cycling

      research Molecular biology of hair morphogenesis: Development and cycling

      155 citations , August 2003 in “Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution”
      This review discusses the conserved molecular mechanisms controlling hair follicle development and cycling and suggests they may also apply to other ectodermal derivatives, like teeth and feathers, but it reports no new results.
      TGF-β Family Signaling in Stem Cells

      research TGF-β family signaling in stem cells

      132 citations , August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”
      This review discusses the roles of TGF-β family signaling in regulating normal and cancer stem cells and highlights the need for further research to develop potential cancer treatments; it reports no new results.
      Cell Death in the Skin: Mechanisms and Implications

      research Cell death in the skin

      120 citations , February 2009 in “Apoptosis”
      This review examines apoptotic and anti-apoptotic mechanisms in skin homeostasis and related diseases but presents no new research findings.
      Genetic Basis of Skin Appendage Development

      research Genetic basis of skin appendage development

      111 citations , January 2007 in “Seminars in cell & developmental biology”
      This article reviews the similarities in early development processes of hair follicles, teeth, and mammary glands and reports no new experimental findings.
      Protection Against Chemotherapy-Induced Alopecia

      research Protection Against Chemotherapy-Induced Alopecia

      97 citations , September 2006 in “Pharmaceutical Research”
      This review discusses advances in protecting against chemotherapy-induced alopecia and reports no new clinical results; calcitriol and cyclosporine A emerged as promising agents in animal models with broader efficacy across multiple chemotherapy drugs.
      Turing Patterns in Development: What About the Horse Part?

      research Turing patterns in development: what about the horse part?

      92 citations , December 2012 in “Current opinion in genetics & development”
      This review covers the recent advances in understanding how Turing models may explain various morphogenetic processes, but it reports no new experimental findings.
      The Blastema and Epimorphic Regeneration in Mammals

      research The blastema and epimorphic regeneration in mammals

      85 citations , December 2017 in “Developmental Biology”
      This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.
      Molecular Basis of Hypohidrotic Ectodermal Dysplasia: An Update

      research Molecular basis of hypohidrotic ectodermal dysplasia: an update

      85 citations , August 2015 in “Journal of Applied Genetics”
      This review discusses recent insights into the molecular mechanisms of hypohidrotic ectodermal dysplasia linked to TNFα-related signaling pathway mutations but reports no new experimental results.
      Development and Homeostasis of the Skin Epidermis

      research Development and Homeostasis of the Skin Epidermis

      85 citations , July 2012 in “Cold Spring Harbor perspectives in biology”
      This article discusses the roles of epidermal stem cells in maintaining skin homeostasis and highlights how deregulation in signaling pathways may lead to cancer, but it reports no new experimental results.
      Molecular Signaling in Feather Morphogenesis

      research Molecular signaling in feather morphogenesis

      85 citations , October 2006 in “Current opinion in cell biology”
      This article reviews advances in feather development and regeneration, including pattern formation, stem cell biology, and evolution, but presents no new experimental results.
      Stem Cells in Tissues, Organoids, and Cancers

      research Stem cells in tissues, organoids, and cancers

      76 citations , July 2019 in “Cellular and Molecular Life Sciences”
      This article reviews the role of stem cells in tissue development, tumor formation, and organoid generation, and highlights the potential of epigenetic regulation in advancing regenerative medicine and cancer treatment, without presenting new experimental results.
      Wnt Signaling in Skin Organogenesis

      research Wnt signaling in skin organogenesis

      72 citations , April 2008 in “Organogenesis”
      This review discusses the roles of Wnt signaling in skin organogenesis and related processes but reports no new experimental results, highlighting areas for future research.
      Regeneration of Skin Appendages and Nerves: Current Status and Further Challenges

      research Regeneration of skin appendages and nerves: current status and further challenges

      71 citations , February 2020 in “Journal of Translational Medicine”
      This article reviews current strategies and advancements in regenerating skin appendages and sensory nerves in tissue-engineered skin, highlighting the challenge of restoring skin sensations like pain, temperature, and touch to improve patients’ quality of life.
      Insulin Resistance and Skin Diseases

      research Insulin Resistance and Skin Diseases

      71 citations , January 2015 in “The Scientific World Journal”
      This review discusses the link between insulin resistance and skin conditions such as acanthosis nigricans and psoriasis, but provides no new clinical results.
      Emerging Nonmetabolic Functions of Skin Fat

      research Emerging nonmetabolic functions of skin fat

      65 citations , January 2018 in “Nature Reviews Endocrinology”
      This review discusses the unique features of dermal white adipose tissue, its interaction with hair follicles, and its role in skin physiology, reporting no new experimental findings.
      Choreographing Immunity in the Skin Epithelial Barrier

      research Choreographing Immunity in the Skin Epithelial Barrier

      57 citations , March 2019 in “Immunity”
      This review discusses the roles of immune responses and cells in skin health and disease, emphasizing recent insights into their mechanisms and potential therapeutic applications, but presents no new experimental results.